3USOA

Crystal structure of leut bound to l-selenomethionine in space group p21212 from lipid bicelles
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Slipknot S +31 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 37-261 225 262-505 1-20 21-36 20 243 slipknot
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41 13-297 285 1-12 346-505 298-345 12 160 slipknot
Chain Sequence
REHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPP---TDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFTLSLGFGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNM
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 13-286 274 1-12 300-502 287-299 12 203 slipknot
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4.1 10-301 292 1-9 311-502 302-310 9 192 slipknot
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3.2 15-327 313 1-14 344-502 328-343 14 159 slipknot
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4.1 12-299 288 1-2, 308-502 3-11, 300-307 2 195 slipknot
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3.2 7-311 305 1-2, 318-502 3-6, 312-317 2 185 slipknot
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1.1 25-271 247 1-15, 285-502 16-24, 272-284 15 218 slipknot
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2.1 32-259 228 1-17, 272-502 18-31, 260-271 17 231 slipknot
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2.1 24-379 356 1-17, 384-502 18-23, 380-383 17 119 slipknot
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2.1 24-412 389 1-17, 427-502 18-23, 413-426 17 76 slipknot
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2.1 40-408 369 409-502 1-18 19-39 18 93 slipknot
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1.1 35-241 207 1-22, 255-502 23-34, 242-254 22 248 slipknot
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2.1 27-273 247 1-24, 283-502 25-26, 274-282 24 220 slipknot
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1.1 41-272 232 1-26, 291-502 27-40, 273-290 26 212 slipknot
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1.1 41-290 250 1-35, 292-502 36-40, 291-291 35 211 slipknot
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3.1 36-264 229 1-31, 271-502 32-35, 265-270 31 232 slipknot
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3.1 41-259 219 1-34, 273-502 35-40, 260-272 34 230 slipknot
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2.1 40-395 356 1-34, 401-502 35-39, 396-400 34 102 slipknot
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1.1 40-242 203 1-35, 251-502 36-39, 243-250 35 252 slipknot
sequence length 505
structure length 502
publication title Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords Transporter
source organism Aquifex aeolicus
missing residues 128-130
total genus Genus: 211
ec nomenclature
pdb deposition date 2011-11-23
KnotProt deposition date 2014-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00209 SNF Sodium:neurotransmitter symporter family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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