| Knot core range | Knot core length | Knot tails range | Slipknot tails range | Slipknot loops range | N-end length | C-end length | Type | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| view details |
 |
+31 | 119-308 | 190 | 1-118 | 436-805 | 309-435 | 118 | 370 | slipknot |
Chain Sequence |
WTNTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKP----------CFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCDSTEERHLLYG----------------RPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE
|
Knotoid cutoff: 0.5
Knotoid matrix content: 1
| Knot core range | Knot core length | Knot tails range | Slipknot tails range | Slipknot loops range | N-end length | C-end length | Type | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| view details |
 |
3.1 | 120-308 | 189 | 1-119 | 426-779 | 309-425 | 119 | 354 | slipknot | ||
| view details |
|
 |
2.1 | 52-425 | 374 | 1-10, 428-779 | 11-51, 426-427 | 10 | 352 | slipknot | ||
| view details |
|
2.1 | 41-305 | 265 | 1-13, 309-779 | 14-40, 306-308 | 13 | 471 | slipknot | |||
| view details |
|
2.1 | 67-305 | 239 | 1-43, 309-779 | 44-66, 306-308 | 43 | 471 | slipknot | |||
| view details |
|
2.1 | 102-306 | 205 | 1-70, 309-779 | 71-101, 307-308 | 70 | 471 | slipknot | |||
| view details |
|
2.1 | 121-358 | 238 | 1-119, 365-779 | 120-120, 359-364 | 119 | 415 | slipknot | |||
| view details |
|
2.1 | 121-402 | 282 | 1-119, 410-779 | 120-120, 403-409 | 119 | 370 | slipknot |
| sequence length |
805
|
| structure length |
779
|
| publication title |
Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe
pubmed doi rcsb |
| molecule tags |
Hydrolase/hydrolase inhibitor
|
| molecule keywords |
Ectonucleotide pyrophosphatase/phosphodiesterase family memb
|
| source organism |
Mus musculus
|
| missing residues |
408-417, 520-535
|
| total genus |
 Genus: 251
|
| ec nomenclature |
ec
3.1.4.39: Alkylglycerophosphoethanolamine phosphodiesterase. |
| pdb deposition date | 2013-05-09 |
| KnotProt deposition date | 2014-10-07 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01033 | Somatomedin_B | Somatomedin B domain |
Image from the rcsb pdb (www.rcsb.org)
#similar chains in the KnotProt database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
