| Knot core range | Knot core length | Knot tails range | Slipknot tails range | Slipknot loops range | N-end length | C-end length | Type | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| view details |
 |
+31 | 121-307 | 187 | 1-120 | 436-805 | 308-435 | 120 | 370 | slipknot |
Chain Sequence |
WTNTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKP----------CFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCDDLEELNHTKGS---TEERHLLY---GRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE
|
Knotoid cutoff: 0.5
Knotoid matrix content: 1
| Knot core range | Knot core length | Knot tails range | Slipknot tails range | Slipknot loops range | N-end length | C-end length | Type | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| view details |
 |
2.1 | 47-306 | 260 | 1-46 | 314-789 | 307-313 | 46 | 476 | slipknot | ||
| view details |
 |
3.1 | 120-308 | 189 | 1-119 | 425-789 | 309-424 | 119 | 365 | slipknot | ||
| view details |
|
|
3.1 | 120-424 | 305 | 1-119 | 426-789 | 425-425 | 119 | 364 | slipknot | |
| view details |
|
|
3.1 | 115-425 | 311 | 1-1, 427-789 | 2-114, 426-426 | 1 | 363 | slipknot | ||
| view details |
|
2.1 | 90-305 | 216 | 1-64, 309-789 | 65-89, 306-308 | 64 | 481 | slipknot | |||
| view details |
|
2.1 | 96-306 | 211 | 1-89, 309-789 | 90-95, 307-308 | 89 | 481 | slipknot |
| sequence length |
805
|
| structure length |
789
|
| publication title |
Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe
pubmed doi rcsb |
| molecule tags |
Hydrolase/hydrolase inhibitor
|
| molecule keywords |
Ectonucleotide pyrophosphatase/phosphodiesterase family memb
|
| source organism |
Mus musculus
|
| missing residues |
408-417, 521-523, 529-531
|
| total genus |
 Genus: 261
|
| ec nomenclature |
ec
3.1.4.39: Alkylglycerophosphoethanolamine phosphodiesterase. |
| pdb deposition date | 2013-05-09 |
| KnotProt deposition date | 2014-10-07 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01033 | Somatomedin_B | Somatomedin B domain |
Image from the rcsb pdb (www.rcsb.org)
#similar chains in the KnotProt database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
