4BXWA

Crystal structure of the prothrombinase complex from the venom of pseudonaja textilis
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 69
Slipknot S -31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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-31 50-278 229 1-49 288-322 279-287 49 35 slipknot
Chain Sequence
CRVDNGNCWHFCKH----IQCSCAEGYLLGEDGHSCVAGGNFSCGRNIKIVNG--------------------------------MDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCINETETISVVVGEIDKSRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVPACLPTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVSSETPITPNMFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGEGCARNGKYGNYTKLSKFIPWIKRIMR
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1m 44-239 196 1-43 245-286 240-244 43 42 slipknot
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3.1m 46-244 199 1-45 251-286 245-250 45 36 slipknot
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2.1m 41-250 210 1-40 255-286 251-254 40 32 slipknot
sequence length 322
structure length 286
publication title Crystal Structure of the Prothrombinase Complex from the Venom of Pseudonaja Textilis.
pubmed doi rcsb
molecule tags Blood clotting
molecule keywords FACTOR XA
source organism Pseudonaja textilis
missing residues 15-18, 50-81
total genus Genus: 69
ec nomenclature
pdb deposition date 2013-07-16
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00008 EGF EGF-like domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling