4D1AA

Structure of mhp1, a nucleobase-cation-symport-1 family transporter, in a closed conformation with indolylmethyl-hydantoin
Slipknot S +31 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 46-222 177 223-456 1-31 32-45 31 233 slipknot
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41 28-260 233 1-27 305-456 261-304 27 152 slipknot
Chain Sequence
SLLNPSNAPTRYAERSVGPFSLAAIWFAMAIQVAIFIAAGQMTSSFQVWQVIVAIAAGCTIAVILLFFTQSAAIRWGINFTVAARMPFGIRGSLIPITLKALLSLFWFGFQTWLGALALDEITRLLTGFTNLPLWIVIFGAIQVVTTFYGITFIRWMNVFASPVLLAMGVYMVYLMLDGADVSLGEVMSMGGENPGMPFSTAIMIFVGGWIAVVVSIHDIVKECKVDPNASREGQTKADARYATAQWLGMVPASIIFGFIGAASMVLVGEWNPVIAITEVVGGVSIPMAILFQVFVLLATWSTNPAANLLSPAYTLCSTFPRVFTFKTGVIVSAVVGLLMMPWQFAGVLNTFLNLLASALGPLAGIMISDYFLVRRRRISLHDLYRTKGIYTYWRGVNWVALAVYAVALAVSFLTPDLMFVTGLIAALLLHIPAMRWVAKTFPLFSEAESRNEDYL
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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4.1 18-272 255 1-17 294-456 273-293 17 163 slipknot
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3.2 22-290 269 1-21 302-456 291-301 21 155 slipknot
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3.2 22-301 280 1-21 305-456 302-304 21 152 slipknot
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4.1 18-269 252 1-9, 273-456 10-17, 270-272 9 184 slipknot
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3.2m 32-283 252 1-17, 300-456 18-31, 284-299 17 157 slipknot
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3.2m 30-299 270 1-21, 302-456 22-29, 300-301 21 155 slipknot
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3.2 32-301 270 1-21, 303-456 22-31, 302-302 21 154 slipknot
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2.1 56-220 165 1-26, 242-456 27-55, 221-241 26 215 slipknot
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2.3 33-244 212 1-26, 260-456 27-32, 245-259 26 197 slipknot
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2.1 53-305 253 1-26, 348-456 27-52, 306-347 26 109 slipknot
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2.1 56-349 294 350-456 1-28 29-55 28 106 slipknot
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2.1 37-244 208 1-32, 254-456 33-36, 245-253 32 203 slipknot
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1.1 41-248 208 1-32, 259-456 33-40, 249-258 32 198 slipknot
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1.1 41-258 218 1-32, 262-456 33-40, 259-261 32 195 slipknot
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1.1 54-244 191 1-36, 262-456 37-53, 245-261 36 195 slipknot
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1.1 53-261 209 1-33, 264-456 34-52, 262-263 33 193 slipknot
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1.1 41-241 201 1-35, 245-456 36-40, 242-244 35 212 slipknot
publication title Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
pubmed doi rcsb
structure length 456
molecule tags Transport protein
source organism Microbacterium liquefaciens
sequence length 456
total genus Genus: 177
molecule keywords HYDANTOIN TRANSPORT PROTEIN
ec nomenclature
pdb deposition date 2014-05-01
KnotProt deposition date 2014-08-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02133 Transp_cyt_pur Permease for cytosine/purines, uracil, thiamine, allantoin
Image from the rcsb pdb (www.rcsb.org)
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