4D1CA

Structure of mhp1, a nucleobase-cation-symport-1 family transporter, in a closed conformation with bromovinylhydantoin bound.
Slipknot S +31 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 52-220 169 221-456 1-29 30-51 29 235 slipknot
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41 28-260 233 1-27 305-456 261-304 27 152 slipknot
Chain Sequence
SLLNPSNAPTRYAERSVGPFSLAAIWFAMAIQVAIFIAAGQMTSSFQVWQVIVAIAAGCTIAVILLFFTQSAAIRWGINFTVAARMPFGIRGSLIPITLKALLSLFWFGFQTWLGALALDEITRLLTGFTNLPLWIVIFGAIQVVTTFYGITFIRWMNVFASPVLLAMGVYMVYLMLDGADVSLGEVMSMGGENPGMPFSTAIMIFVGGWIAVVVSIHDIVKECKVDPNASREGQTKADARYATAQWLGMVPASIIFGFIGAASMVLVGEWNPVIAITEVVGGVSIPMAILFQVFVLLATWSTNPAANLLSPAYTLCSTFPRVFTFKTGVIVSAVVGLLMMPWQFAGVLNTFLNLLASALGPLAGIMISDYFLVRRRRISLHDLYRTKGIYTYWRGVNWVALAVYAVALAVSFLTPDLMFVTGLIAALLLHIPAMRWVAKTFPLFSEAESRNEDYL
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 22-253 232 1-21 268-456 254-267 21 189 slipknot
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4.1 20-272 253 1-19 296-456 273-295 19 161 slipknot
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3.2 18-295 278 1-17 300-456 296-299 17 157 slipknot
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3.2 20-295 276 1-19 305-456 296-304 19 152 slipknot
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4.1 23-265 243 1-2, 271-456 3-22, 266-270 2 186 slipknot
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4.1 22-270 249 1-2, 273-456 3-21, 271-272 2 184 slipknot
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3.2 21-272 252 1-19, 276-456 20-20, 273-275 19 181 slipknot
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3.2 31-281 251 1-19, 298-456 20-30, 282-297 19 159 slipknot
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3.2 32-281 250 1-30, 298-456 31-31, 282-297 30 159 slipknot
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1.1 30-252 223 1-23, 265-456 24-29, 253-264 23 192 slipknot
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3.2 30-271 242 1-24, 278-456 25-29, 272-277 24 179 slipknot
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2.1 49-305 257 1-28, 347-456 29-48, 306-346 28 110 slipknot
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2.1 58-350 293 351-456 1-28 29-57 28 105 slipknot
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2.1 44-221 178 1-29, 247-456 30-43, 222-246 29 210 slipknot
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1.1 53-245 193 1-33, 263-456 34-52, 246-262 33 194 slipknot
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2.1 55-217 163 1-44, 243-456 45-54, 218-242 44 214 slipknot
publication title Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
pubmed doi rcsb
structure length 456
molecule tags Transport protein
source organism Microbacterium liquefaciens
sequence length 456
total genus Genus: 178
molecule keywords HYDANTOIN TRANSPORT PROTEIN
ec nomenclature
pdb deposition date 2014-05-01
KnotProt deposition date 2014-08-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02133 Transp_cyt_pur Permease for cytosine/purines, uracil, thiamine, allantoin
Image from the rcsb pdb (www.rcsb.org)
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