4GTYA

Crystal structure of mouse enpp1 in complex with gmp
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 31-236 206 1-30 360-733 237-359 30 374 slipknot
Chain Sequence
KSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIPAPNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIKSTSNDLGCTCDP----------------EDDDIYHMTVPYGRPRILLKQHRVCLLQQQQFLTGYSLDLLMPLWASYTFLSNDSNCLYQDLRIPLSPVH-------KCSYYKSNSKLSYGFLTPPRLNHIYSEALLTSNIVPMYQSFQVIW----HYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILKQNSRVIRSQEILIPTHFFIVLTSCKQLSETPLECSALESSAYILPHRPDNIESCTHGKRESSWVEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFS
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 13-234 222 1-12 240-706 235-239 12 467 slipknot
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3.1 31-235 205 1-30 319-706 236-318 30 388 slipknot
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3.1 31-318 288 1-30 352-706 319-351 30 355 slipknot
view details
3.1 31-351 321 1-30 359-706 352-358 30 348 slipknot
sequence length 733
structure length 706
publication title Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family memb
source organism Mus musculus
missing residues 443-458, 513-519, 558-561
total genus Genus: 197
ec nomenclature ec 3.1.4.1: Phosphodiesterase I.
ec 3.1.4.39: Alkylglycerophosphoethanolamine phosphodiesterase.
ec 3.6.1.9: Nucleotide diphosphatase.
pdb deposition date 2012-08-29
KnotProt deposition date 2014-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01033 Somatomedin_B Somatomedin B domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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