4GTZA

Crystal structure of mouse enpp1 in complex with cmp
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 30-236 207 1-29 359-733 237-358 29 375 slipknot
Chain Sequence
KSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIPAPNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIKSTSNDLGCTCDP----------------EDDDIYHMTVPYGRPRILLKQHRVCLLQQQQFLTGYSLDLLMPLWASYTFLSNDSNCLYQDLRIPLSPVH-------KCSYYKSNSKLSYGFLTPPRLNHIYSEALLTSNIVPMYQSFQVIW----HYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILKQNSRVIRSQEILIPTHFFIVLTSCKQLSETPLECSALESSAYILPHRPDNIESCTHGKRESSWVEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFS
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1 25-234 210 1-24 241-706 235-240 24 466 slipknot
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3.1 29-237 209 1-28 346-706 238-345 28 361 slipknot
view details
3.1 29-345 317 1-28 358-706 346-357 28 349 slipknot
view details
3.1 29-357 329 1-28 359-706 358-358 28 348 slipknot
sequence length 733
structure length 706
publication title Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family memb
source organism Mus musculus
missing residues 443-458, 513-519, 558-561
total genus Genus: 196
ec nomenclature ec 3.1.4.1: Phosphodiesterase I.
ec 3.1.4.39: Alkylglycerophosphoethanolamine phosphodiesterase.
ec 3.6.1.9: Nucleotide diphosphatase.
pdb deposition date 2012-08-29
KnotProt deposition date 2014-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01033 Somatomedin_B Somatomedin B domain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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