4HODA

Crystal structure of leut-e290s with bound cl
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 208
Slipknot S +31 41 +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 40-263 224 264-511 1-19 20-39 19 247 slipknot
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41 14-293 280 1-13 347-511 294-346 13 165 slipknot
Chain Sequence
REHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPPP--TDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFTLSLGFGAIITYASYVRKDQDIVLSGLTAATLNEKASVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNHESAGT
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2m 11-288 278 1-10 301-509 289-300 10 209 slipknot
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3.2 11-300 290 1-10 308-509 301-307 10 202 slipknot
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4.1 11-307 297 1-10 317-509 308-316 10 193 slipknot
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3.2 12-333 322 1-11 349-509 334-348 11 161 slipknot
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4.1 9-326 318 1-3, 333-509 4-8, 327-332 3 177 slipknot
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4.1 12-299 288 1-10, 308-509 11-11, 300-307 10 202 slipknot
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2.1 31-254 224 1-15, 267-509 16-30, 255-266 15 243 slipknot
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2.1 42-405 364 406-509 1-16 17-41 16 103 slipknot
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2.1 42-353 312 1-18, 401-509 19-41, 354-400 18 109 slipknot
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1.1 30-273 244 1-19, 282-509 20-29, 274-281 19 228 slipknot
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2.1 29-268 240 1-22, 274-509 23-28, 269-273 22 236 slipknot
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2.1 33-252 220 1-23, 258-509 24-32, 253-257 23 252 slipknot
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1.1 40-243 204 1-24, 256-509 25-39, 244-255 24 254 slipknot
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2.1 41-278 238 1-26, 295-509 27-40, 279-294 26 215 slipknot
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1.1 42-261 220 1-30, 274-509 31-41, 262-273 30 236 slipknot
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1.1 44-278 235 1-40, 295-509 41-43, 279-294 40 215 slipknot
sequence length 511
structure length 509
publication title The chloride binding site of Neurotransmitter Sodium Symporters
rcsb
molecule tags Membrane protein
molecule keywords Transporter
source organism Aquifex aeolicus
missing residues 129-130
total genus Genus: 208
ec nomenclature
pdb deposition date 2012-10-22
KnotProt deposition date 2014-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00209 SNF Sodium:neurotransmitter symporter family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling