| Knot core range | Knot core length | Knot tails range | Slipknot tails range | Slipknot loops range | N-end length | C-end length | Type | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| view details |
 |
+31 | 20-255 | 236 | 1-19, 256-258 | 19 | 3 | knot |
Chain Sequence |
HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFDFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
|
| Knot core range | Knot core length | Knot tails range | Slipknot tails range | Slipknot loops range | N-end length | C-end length | Type | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
+ 31 | 24-255 | 232 | 1-23, 256-258 | 23 | 3 | knot |
| Fingerprint | Knot forming loop | Loop type | ||||
|---|---|---|---|---|---|---|
|
|
K +31 | His4 ... Val135 <-> Bridging ionMbo302 <-> Gln137 ... Chain closureLys261 <-> His4 |
probabilistic | |||
|
|
K +31 | His4 ... Asp94 <-> Bridging ionZn301 <-> His96 ... Chain closureLys261 <-> His4 |
probabilistic | |||
|
|
K +31 | His4 ... His96 <-> Bridging ionZn301 <-> His119 ... Chain closureLys261 <-> His4 |
probabilistic | |||
|
|
K +31 | His4 ... Asp94 <-> Bridging ionZn301 <-> His119 ... Chain closureLys261 <-> His4 |
probabilistic | |||
|
|
K +31 | His4 ... Val135 <-> Bridging ionMbo302 <-> Cys206 ... Chain closureLys261 <-> His4 |
probabilistic | |||
|
|
K +31 | Chain closureHis4 <-> Lys261 ... Cys206 <-> Bridging ionMbo302 <-> Gln137 ... His4 |
probabilistic | |||
|
|
K +31 | His4 ... Asp94 <-> Bridging ionZn301 <-> His96 ... Val135 <-> Bridging ionMbo302 <-> Gln137 ... Chain closureLys261 <-> His4 |
probabilistic | |||
|
|
K +31 | His4 ... His96 <-> Bridging ionZn301 <-> His119 ... Val135 <-> Bridging ionMbo302 <-> Gln137 ... Chain closureLys261 <-> His4 |
probabilistic | |||
|
|
K +31 | His4 ... Asp94 <-> Bridging ionZn301 <-> His119 ... Val135 <-> Bridging ionMbo302 <-> Gln137 ... Chain closureLys261 <-> His4 |
probabilistic | |||
|
|
K +31 | His4 ... Asp94 <-> Bridging ionZn301 <-> His96 ... Val135 <-> Bridging ionMbo302 <-> Cys206 ... Chain closureLys261 <-> His4 |
probabilistic | |||
|
|
K +31 | His4 ... His96 <-> Bridging ionZn301 <-> His119 ... Val135 <-> Bridging ionMbo302 <-> Cys206 ... Chain closureLys261 <-> His4 |
probabilistic | |||
|
|
K +31 | His4 ... Asp94 <-> Bridging ionZn301 <-> His119 ... Val135 <-> Bridging ionMbo302 <-> Cys206 ... Chain closureLys261 <-> His4 |
probabilistic | |||
|
|
K +31 | Chain closureHis4 <-> Lys261 ... Cys206 <-> Bridging ionMbo302 <-> Gln137 ... His96 <-> Bridging ionZn301 <-> Asp94 ... His4 |
probabilistic | |||
|
|
K +31 | Chain closureHis4 <-> Lys261 ... Cys206 <-> Bridging ionMbo302 <-> Gln137 ... His119 <-> Bridging ionZn301 <-> His96 ... His4 |
probabilistic | |||
|
|
K +31 | Chain closureHis4 <-> Lys261 ... Cys206 <-> Bridging ionMbo302 <-> Gln137 ... His119 <-> Bridging ionZn301 <-> Asp94 ... His4 |
probabilistic |
Chain Sequence |
HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFDFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
|
Knotoid cutoff: 0.5
Knotoid matrix content: 1
| Knot core range | Knot core length | Knot tails range | Slipknot tails range | Slipknot loops range | N-end length | C-end length | Type | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| view details |
 |
3.1 | 24-256 | 233 | 1-23, 257-257 | 23 | 1 | knot | ||||
| view details |
 |
2.1 | 24-251 | 228 | 1-23 | 257-257 | 252-256 | 23 | 1 | slipknot | ||
| view details |
|
3.1 | 25-255 | 231 | 256-257 | 1-23 | 24-24 | 23 | 1 | slipknot |
| sequence length |
257
|
| structure length |
257
|
| publication title |
Metalloprotein-Inhibitor Binding: Human Carbonic Anhydrase II as a Model for Probing Metal-Ligand Interactions in a Metalloprotein Active Site.
pubmed doi rcsb |
| molecule tags |
Lyase
|
| molecule keywords |
Carbonic anhydrase 2
|
| source organism |
Homo sapiens
|
| total genus |
 Genus: 74
|
| ec nomenclature |
ec
4.2.1.1: Carbonate dehydratase. |
| pdb deposition date | 2013-03-22 |
| KnotProt deposition date | 2018-10-19 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00194 | Carb_anhydrase | Eukaryotic-type carbonic anhydrase |
Image from the rcsb pdb (www.rcsb.org)
#similar chains in the KnotProt database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
