4K0BA

Crystal structure of s-adenosylmethionine synthetase from sulfolobus solfataricus complexed with sam and ppi
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 26-291 266 1-25, 292-404 25 113 knot
Chain Sequence
MRNINVQLNPLSDIEKLQVELVERKGLGHPDYIADAVAEEASRKLSLYYLKKYGVILHHNLDKTLVVGGQATPRFKGGDIIQPIYIIVAGRATTEVKTESGIDQIPVGTIIIESVKEWIRNNFRYLDAERHVIVDYKIGKGSSDLVGIFEASKRVPLSNDTSFGVGFAPLTKLEKLVYETERHLNSKQFKAKLPEVGEDIKVMGLRRGNEVDLTIAMATISELIEDVNHYINVKEQVRNQILDLASKIAPGYNVRVYVNTGDKIDKNILYLTVTGTSAEHGDDGMTGRGNRGVGLITPMRPMSLEATAGKNPVNHVGKLYNVLANLIANKIAQEVKDVKFSQVQVLGQIGRPIDDPLIANVDVITYDGKLTDETKNEISGIVDEMLSSFNKLTELILEGKATLF
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.1 20-399 380 1-19, 400-404 19 5 knot
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2.1 22-284 263 1-21 298-404 285-297 21 107 slipknot
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3.1 23-321 299 1-22 391-404 322-390 22 14 slipknot
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3.1 23-390 368 1-22 395-404 391-394 22 10 slipknot
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3.1 23-394 372 1-22 400-404 395-399 22 5 slipknot
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3.1 22-399 378 1-19, 404-404 20-21, 400-403 19 1 slipknot
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2.1 33-325 293 1-22, 391-404 23-32, 326-390 22 14 slipknot
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2.1 32-390 359 1-22, 392-404 23-31, 391-391 22 13 slipknot
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2.1 32-391 360 1-22, 397-404 23-31, 392-396 22 8 slipknot
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2.1 34-320 287 1-20, 332-404 21-33, 321-331 20 73 slipknot
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2.1 35-332 298 1-32, 387-404 33-34, 333-386 32 18 slipknot
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2.1 35-391 357 1-31, 397-404 32-34, 392-396 31 8 slipknot
sequence length 404
structure length 404
publication title Understanding Molecular Recognition of Promiscuity of Thermophilic Methionine Adenosyltransferase, sMAT from Sulfolobus solfataricus.
pubmed doi rcsb
molecule tags Transferase
molecule keywords S-adenosylmethionine synthase
source organism Sulfolobus solfataricus
total genus Genus: 140
ec nomenclature ec 2.5.1.6: Methionine adenosyltransferase.
pdb deposition date 2013-04-03
KnotProt deposition date 2014-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01941 AdoMet_Synthase S-adenosylmethionine synthetase (AdoMet synthetase)
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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