4K1CA

Vcx1 calcium/proton exchanger
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 152
Knot K +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 57-304 248 1-56, 305-380 56 76 knot
Chain Sequence
TAWRAAVYDLQYILKASPLNFLLVFVPLGLIWGHFQLSHTLTFLFNFLAIIPLAAILANATEELADKAGNTIGGLLNATFGNAVELIVSIIALKKGQVRIVQASMLGSLLSNLLLVLGLCFIFGGYNRVQQTFNQTAAQTMSSLLAIACASLLIPAAFRATLP------FIDGKILELSRGTSIVILIVYVLFLYFQLGSHHALFEQQEEETDEVMSTISRNPHHSLSVKSSLVILLGTTVIISFCADFLVGTIDNVVESTGLSKTFIGLIVIPIVGNAAEHVTSVLVAMKDKMDLALGVAIGSSLQVALFVTPFMVLVGWMIDVPMTLNFSTFETATLFIAVFLSNYLILDGESNWLEGVMSLAMYILIAMAFFYYPDE
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.1 13-324 312 1-12 358-374 325-357 12 17 slipknot
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2.1 22-328 307 329-374 1-9 10-21 9 45 slipknot
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2.1 30-328 299 329-374 1-21 22-29 21 45 slipknot
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3.1 28-311 284 1-13, 329-374 14-27, 312-328 13 46 slipknot
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3.1 42-327 286 1-27, 370-374 28-41, 328-369 27 5 slipknot
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3.1 42-369 328 370-374 1-29 30-41 29 4 slipknot
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3.1 50-350 301 351-374 1-41 42-49 41 23 slipknot
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2.1 43-327 285 1-41, 351-374 42-42, 328-350 41 24 slipknot
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2.1 36-311 276 1-27, 328-374 28-35, 312-327 27 47 slipknot
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3.1 48-327 280 1-42, 351-374 43-47, 328-350 42 24 slipknot
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3.1 40-313 274 1-35, 328-374 36-39, 314-327 35 47 slipknot
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2.1 42-313 272 1-39, 328-374 40-41, 314-327 39 47 slipknot
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2.1 61-306 246 307-374 1-35 36-60 35 67 slipknot
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2.1 64-310 247 311-374 1-60 61-63 60 63 slipknot
sequence length 380
structure length 374
publication title Structural basis for alternating access of a eukaryotic calcium/proton exchanger.
pubmed doi rcsb
molecule tags Membrane protein/metal transport
molecule keywords Vacuolar calcium ion transporter
source organism Saccharomyces cerevisiae
missing residues 164-169
total genus Genus: 152
ec nomenclature
pdb deposition date 2013-04-04
KnotProt deposition date 2014-07-31
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling