4KJRA

Crystal structure of selenium substituted ca2+/h+ antiporter proteinyfke
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 92
Knot K +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 48-274 227 1-47, 275-350 47 76 knot
Chain Sequence
NRIFFILVAAGVPLSVIGSLMHWPSAVLFAVYCVTIIALASYMGRATESLSII---RIGGLLNATFGNAVELIISMFALKEGLTGIVLASLTGSVLGNLLLVAGLSFFVGGLKYARQEFNIHDARHNSGLLIFAIIVAFVIPEVFSVGMGNASKLNLSIGISIIMILLYVAALYFKEWS----------------------GKVATIVLFAATIVVAYISENLVHTFHSVAEQFGWSELFIGVIIVAIVGNAAEHASAIIMAFKNKMDIAVEIAVGSTLQIAMFVAPVLVICSIFFPTSMPLVFTLPELVAMVSAVLLMIAISNDGDSNWFEGATLLAAYVIMAIGFFLL
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.1 31-303 273 1-30, 304-325 30 22 knot
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2.1 28-268 241 1-2, 287-325 3-27, 269-286 2 39 slipknot
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3.1 28-286 259 1-2, 302-325 3-27, 287-301 2 24 slipknot
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3.1 29-283 255 1-27, 302-325 28-28, 284-301 27 24 slipknot
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3.1 32-303 272 304-325 1-30 31-31 30 21 slipknot
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3.1 42-286 245 1-9, 310-325 10-41, 287-309 9 16 slipknot
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2.1 42-309 268 1-31, 317-325 32-41, 310-316 31 9 slipknot
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3.1 33-283 251 1-28, 287-325 29-32, 284-286 28 39 slipknot
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3.1 37-316 280 317-325 1-31 32-36 31 8 slipknot
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2.1 50-264 215 265-325 1-25 26-49 25 60 slipknot
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2.1 51-272 222 273-325 1-49 50-50 49 52 slipknot
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2.1 73-303 231 304-325 1-58 59-72 58 21 slipknot
sequence length 350
structure length 325
publication title Crystal structure of Ca2+/H+ antiporter protein YfkE reveals the mechanisms of Ca2+ efflux and its pH regulation.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords cation exchanger YfkE
source organism Bacillus subtilis subsp. subtilis
missing residues 54-56, 177-198
total genus Genus: 92
ec nomenclature
pdb deposition date 2013-05-03
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01699 Na_Ca_ex Sodium/calcium exchanger protein
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling