4KY9A

Structural and functional analysis of a putative substrate access tunnel in the cytosolic domain of human anion exchanger 1
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 85
Slipknot S -31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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-31 39-177 139 1-33, 220-294 34-38, 178-219 33 75 slipknot
Chain Sequence
VYVELQELVMDEKNQELRWMEAARWVQLEENLGENGAWGRPHLSHLTFWSLLELRRVFTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHAGELEALGGVKPAVLTR---PSQPLLPQHSSLETQLFCEEKI---------------PPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAVELPVPIRFLFVLLGPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSEQALLSLVPVQRELLRRRYQSS
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1m 5-158 154 1-4 165-276 159-164 4 112 slipknot
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2.1m 25-159 135 1-21, 165-276 22-24, 160-164 21 112 slipknot
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2.1m 40-154 115 1-29, 170-276 30-39, 155-169 29 107 slipknot
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2.1m 40-191 152 1-30, 210-276 31-39, 192-209 30 67 slipknot
sequence length 294
structure length 276
publication title A Substrate Access Tunnel in the Cytosolic Domain is not an Essential Feature of the SLC4 Family of Bicarbonate Transporters
doi rcsb
molecule tags Membrane protein
molecule keywords Band 3 anion transport protein
source organism Homo sapiens
missing residues 125-127, 147-161
total genus Genus: 85
ec nomenclature
pdb deposition date 2013-05-28
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07565 Band_3_cyto Band 3 cytoplasmic domain
Image from the rcsb pdb (www.rcsb.org)
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling