4L2ZA

Crystal structure of s-adenosylmethionine synthetase from sulfolobus solfataricus complexed with sae and ppi
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 25-291 267 1-24, 292-404 24 113 knot
Chain Sequence
MRNINVQLNPLSDIEKLQVELVERKGLGHPDYIADAVAEEASRKLSLYYLKKYGVILHHNLDKTLVVGGQATPRFKGGDIIQPIYIIVAGRATTEVKTESGIDQIPVGTIIIESVKEWIRNNFRYLDAERHVIVDYKIGKGSSDLVGIFEASKRVPLSNDTSFGVGFAPLTKLEKLVYETERHLNSKQFKAKLPEVGEDIKVMGLRRGNEVDLTIAMATISELIEDVNHYINVKEQVRNQILDLASKIAPGYNVRVYVNTGDKIDKNILYLTVTGTSAEHGDDGMTGRGNRGVGLITPMRPMSLEATAGKNPVNHVGKLYNVLANLIANKIAQEVKDVKFSQVQVLGQIGRPIDDPLIANVDVITYDGKLTDETKNEISGIVDEMLSSFNKLTELILEGKATLF
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.1 22-393 372 1-21, 394-404 21 11 knot
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2.1 23-284 262 1-22 298-404 285-297 22 107 slipknot
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3.1 23-321 299 1-22 394-404 322-393 22 11 slipknot
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1.1 34-305 272 1-16, 328-404 17-33, 306-327 16 77 slipknot
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2.1 34-327 294 1-22, 348-404 23-33, 328-347 22 57 slipknot
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2.1 34-347 314 1-22, 388-404 23-33, 348-387 22 17 slipknot
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2.1 33-387 355 1-22, 390-404 23-32, 388-389 22 15 slipknot
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2.1 34-389 356 1-22, 392-404 23-33, 390-391 22 13 slipknot
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2.1 33-391 359 1-21, 397-404 22-32, 392-396 21 8 slipknot
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2.1 34-391 358 1-32, 397-404 33-33, 392-396 32 8 slipknot
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2.1 35-329 295 1-33, 345-404 34-34, 330-344 33 60 slipknot
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2.1 35-355 321 1-33, 388-404 34-34, 356-387 33 17 slipknot
publication title Understanding Molecular Recognition of Promiscuity of Thermophilic Methionine Adenosyltransferase, sMAT from Sulfolobus solfataricus.
pubmed doi rcsb
structure length 404
molecule tags Transferase
source organism Sulfolobus solfataricus
sequence length 404
total genus Genus: 140
molecule keywords S-adenosylmethionine synthase
ec nomenclature ec 2.5.1.6: Methionine adenosyltransferase.
pdb deposition date 2013-06-05
KnotProt deposition date 2014-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01941 AdoMet_Synthase S-adenosylmethionine synthetase (AdoMet synthetase)
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the pdb database (?% sequence similarity)

 
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