4L4QA

Methionine adenosyltransferase
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 33-287 255 1-32, 288-402 32 115 knot
Chain Sequence
KVRNIVVEELVRTPVEMQKVELVERKGIGHPDSIADGIAEAVSRALSREYVKRYGIILHHNTDQVEVVGGRAYPQFGGGEVIKPIYILLSGRAVEMVDREFFPVHEIALKAAKDYLRKAVRHLDLEHHVIIDSRIGQGSVDLVGVFNKAKKNPIPLANDTSFGVGYAPLSETEKIVLETEKYLNSDEFKKKYPAVGEDIKVMGLRKGDEIDLTIAAAIVDSEVDNPDDYMAVKEAIYEAAKGIVESHTERPTNIYVNTADDPKEGIYYITVTGTSAEAGDDGSVGRGNRVNGLITPNRHMSMEAAAGKNPVSHVGKIYNILSMLIANDIAEQVEGVEEVYVRILSQIGKPIDEPLVASVQIIPKKGYSIDVLQKPAYEIADEWLANITKIQKMILEDKVNVF
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1 22-389 368 1-21, 390-402 21 13 knot
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2.1 24-283 260 1-23 297-402 284-296 23 106 slipknot
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3.1 24-323 300 1-23 390-402 324-389 23 13 slipknot
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2.1 27-300 274 1-2, 324-402 3-26, 301-323 2 79 slipknot
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2.1 27-323 297 1-23, 325-402 24-26, 324-324 23 78 slipknot
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2.1 27-324 298 1-23, 335-402 24-26, 325-334 23 68 slipknot
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3.1 23-389 367 390-402 1-21 22-22 21 12 slipknot
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1.1 32-302 271 1-26, 325-402 27-31, 303-324 26 78 slipknot
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2.1 32-324 293 1-26, 335-402 27-31, 325-334 26 68 slipknot
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2.1 32-334 303 1-23, 382-402 24-31, 335-381 23 21 slipknot
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2.1 34-323 290 1-23, 389-402 24-33, 324-388 23 14 slipknot
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2.1 34-388 355 1-22, 391-402 23-33, 389-390 22 12 slipknot
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2.1 34-390 357 1-22, 392-402 23-33, 391-391 22 11 slipknot
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2.1 35-316 282 1-31, 335-402 32-34, 317-334 31 68 slipknot
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2.1 35-335 301 1-33, 382-402 34-34, 336-381 33 21 slipknot
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2.1 36-329 294 1-34, 382-402 35-35, 330-381 34 21 slipknot
sequence length 402
structure length 402
publication title Structural and functional characterisation of the methionine adenosyltransferase from Thermococcus kodakarensis.
pubmed doi rcsb
molecule tags Transferase
molecule keywords S-adenosylmethionine synthase
source organism Thermococcus kodakarensis
total genus Genus: 149
ec nomenclature ec 2.5.1.6: Methionine adenosyltransferase.
pdb deposition date 2013-06-09
KnotProt deposition date 2014-08-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01941 AdoMet_Synthase S-adenosylmethionine synthetase (AdoMet synthetase)
Image from the rcsb pdb (www.rcsb.org)
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