4L7IA

Crystal structure of s-adenosylmethionine synthase from sulfolobus solfataricus complexed with sam and ppi
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 30-290 261 1-29, 291-404 29 114 knot
Chain Sequence
MRNINVQLNPLSDIEKLQVELVERKGLGHPDYIADAVAEEASRKLSLYYLKKYGVILHHNLDKTLVVGGQATPRFKGGDIIQPIYIIVAGRATTEVKTESGIDQIPVGTIIIESVKEWIRNNFRYLDAERHVIVDYKIGKGSSDLVGIFEASKRVPLSNDTSFGVGFAPLTKLEKLVYETERHLNSKQFKAKLPEVGEDIKVMGLRRGNEVDLTIAMATISELIEDVNHYINVKEQVRNQILDLASKIAPGYNVRVYVNTGDKIDKNILYLTVTGTSAEHGDDGMTGRGNRGVGLITPMRPMSLEATAGKNPVNHVGKLYNVLANLIANKIAQEVKDVKFSQVQVLGQIGRPIDDPLIANVDVITYDGKLTDETKNEISGIVDEMLSSFNKLTELILEGKATLF
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1 19-397 379 1-18, 398-404 18 7 knot
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2.1 22-284 263 1-21 298-404 285-297 21 107 slipknot
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3.1 24-323 300 1-23 396-404 324-395 23 9 slipknot
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3.1 23-395 373 1-22 398-404 396-397 22 7 slipknot
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2.1 33-320 288 1-18, 390-404 19-32, 321-389 18 15 slipknot
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2.1 33-389 357 1-23, 394-404 24-32, 390-393 23 11 slipknot
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2.1 33-393 361 1-18, 401-404 19-32, 394-400 18 4 slipknot
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2.1 31-304 274 1-19, 321-404 20-30, 305-320 19 84 slipknot
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2.1 34-323 290 1-32, 388-404 33-33, 324-387 32 17 slipknot
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2.1 34-390 357 1-32, 394-404 33-33, 391-393 32 11 slipknot
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2.1 35-328 294 1-33, 371-404 34-34, 329-370 33 34 slipknot
publication title Understanding Molecular Recognition of Promiscuity of Thermophilic Methionine Adenosyltransferase, sMAT from Sulfolobus solfataricus.
pubmed doi rcsb
structure length 404
molecule tags Transferase
source organism Sulfolobus solfataricus
sequence length 404
total genus Genus: 143
molecule keywords S-adenosylmethionine synthase
ec nomenclature ec 2.5.1.6: Methionine adenosyltransferase.
pdb deposition date 2013-06-13
KnotProt deposition date 2014-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01941 AdoMet_Synthase S-adenosylmethionine synthetase (AdoMet synthetase)
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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