4OQLA

Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with df-edu
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 113
Slipknot S +31

  Help Knotting data interpretation Full screen
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 5-117 113 1-4 304-329 118-303 4 26 slipknot
Chain Sequence
MPTLLRVYIDGPHGMGKTTTTQLLVA---RDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITMGMPYAVTDAVLAPHIGGEAPPP-----ALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRQRPGERLDLAMLAAIRRVYGLLANTVRYLQCGGSWREDWGQLSGPRPHIGDT---------------LFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRSMHVFILDYDQSPAGCRDALLQLTSGMVQTHVTTPGSIPTICDLARTFAREMGE
Whole chain analysis

  Help Knotoid data interpretation Full screen
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


  Help Knotoid subchains data interpretation Full screen
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 8-110 103 1-7 147-306 111-146 7 160 slipknot
view details
3.1 4-146 143 1-3 166-306 147-165 3 141 slipknot
view details
2.1 8-147 140 1-7 279-306 148-278 7 28 slipknot
view details
3.1 4-278 275 1-3 282-306 279-281 3 25 slipknot
view details
2.1 9-159 151 1-7, 271-306 8-8, 160-270 7 36 slipknot
sequence length 329
structure length 306
publication title Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with dF-EdU
rcsb
molecule tags Transferase
molecule keywords Thymidine kinase
source organism Human herpesvirus 1
missing residues 27-29, 103-107, 220-234
total genus Genus: 113
ec nomenclature ec 2.7.1.21: Thymidine kinase.
pdb deposition date 2014-02-10
KnotProt deposition date 2014-08-16
Image from the rcsb pdb (www.rcsb.org)
...loading similar chains, please wait...
similar chains in the KnotProt database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the KnotProt database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling