4OQLA

Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with df-edu
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 5-117 113 1-4 304-329 118-303 4 26 slipknot
Chain Sequence
MPTLLRVYIDGPHGMGKTTTTQLLVA---RDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITMGMPYAVTDAVLAPHIGGEAPPP-----ALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRQRPGERLDLAMLAAIRRVYGLLANTVRYLQCGGSWREDWGQLSGPRPHIGDT---------------LFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRSMHVFILDYDQSPAGCRDALLQLTSGMVQTHVTTPGSIPTICDLARTFAREMGE
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 8-110 103 1-7 147-306 111-146 7 160 slipknot
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3.1 4-146 143 1-3 166-306 147-165 3 141 slipknot
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2.1 8-147 140 1-7 279-306 148-278 7 28 slipknot
view details
3.1 4-278 275 1-3 282-306 279-281 3 25 slipknot
view details
2.1 9-159 151 1-7, 271-306 8-8, 160-270 7 36 slipknot
missing residues 27-29, 103-107, 220-234
publication title Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with dF-EdU
rcsb
structure length 306
molecule tags Transferase
source organism Human herpesvirus 1
sequence length 329
total genus Genus: 113
molecule keywords Thymidine kinase
ec nomenclature ec 2.7.1.21: Thymidine kinase.
pdb deposition date 2014-02-10
KnotProt deposition date 2014-08-16
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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