4P19A

Closed, apo inward-facing state of the glutamate transporter homologue gltph
Genus: 158
Slipknot S +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 52-320 269 1-51 339-414 321-338 51 76 slipknot
Chain Sequence
YIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLCMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVATFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLCMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTEGTLV
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1 43-307 265 1-42 345-414 308-344 42 70 slipknot
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2.1 37-358 322 1-27, 366-414 28-36, 359-365 27 49 slipknot
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2.1 52-326 275 1-44, 340-414 45-51, 327-339 44 75 slipknot
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1.1 60-328 269 1-47, 341-414 48-59, 329-340 47 74 slipknot
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1.1 59-314 256 1-48, 328-414 49-58, 315-327 48 87 slipknot
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2.1 59-327 269 1-51, 329-414 52-58, 328-328 51 86 slipknot
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1.1 61-328 268 1-59, 341-414 60-60, 329-340 59 74 slipknot
sequence length 414
structure length 414
publication title Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords 425aa long hypothetical proton glutamate symport protein
source organism Pyrococcus horikoshii
total genus Genus: 158
ec nomenclature
pdb deposition date 2014-02-25
KnotProt deposition date 2014-08-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00375 SDF Sodium:dicarboxylate symporter family
Image from the rcsb pdb (www.rcsb.org)
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling