4P19B

Closed, apo inward-facing state of the glutamate transporter homologue gltph
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 46-321 276 1-45 336-408 322-335 45 73 slipknot
Chain Sequence
EYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLCMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVATFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLCMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTE
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1 44-306 263 1-43 343-408 307-342 43 66 slipknot
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2.1 30-355 326 1-18, 363-408 19-29, 356-362 18 46 slipknot
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1.1 57-314 258 1-43, 323-408 44-56, 315-322 43 86 slipknot
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2.1 53-322 270 1-44, 325-408 45-52, 323-324 44 84 slipknot
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2.1 53-324 272 1-45, 328-408 46-52, 325-327 45 81 slipknot
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2.1 57-326 270 1-47, 341-408 48-56, 327-340 47 68 slipknot
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1.1 59-326 268 1-56, 341-408 57-58, 327-340 56 68 slipknot
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1.1 57-357 301 1-50, 364-408 51-56, 358-363 50 45 slipknot
sequence length 408
structure length 408
publication title Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords 425aa long hypothetical proton glutamate symport protein
source organism Pyrococcus horikoshii
ec nomenclature
pdb deposition date 2014-02-25
KnotProt deposition date 2014-08-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00375 SDF Sodium:dicarboxylate symporter family
Image from the rcsb pdb (www.rcsb.org)
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