4P6HA

Tl+-bound inward-facing state (bound conformation) of the glutamate transporter homologue gltph
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 47-320 274 1-46 338-410 321-337 46 73 slipknot
Chain Sequence
YIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLCMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVATFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLCMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTE
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 46-311 266 1-45 345-410 312-344 45 66 slipknot
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2.1 38-356 319 1-15, 367-410 16-37, 357-366 15 44 slipknot
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1.1 49-333 285 1-45, 340-410 46-48, 334-339 45 71 slipknot
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1.1 57-329 273 1-47, 341-410 48-56, 330-340 47 70 slipknot
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2.1 59-316 258 1-51, 327-410 52-58, 317-326 51 84 slipknot
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1.1 58-360 303 1-52, 365-410 53-57, 361-364 52 46 slipknot
publication title Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
pubmed doi rcsb
structure length 410
molecule tags Transport protein
source organism Pyrococcus horikoshii
sequence length 410
total genus Genus: 138
molecule keywords GltPh
ec nomenclature
pdb deposition date 2014-03-24
KnotProt deposition date 2014-08-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00375 SDF Sodium:dicarboxylate symporter family
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the pdb database (?% sequence similarity)

 
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