4P6HB

Tl+-bound inward-facing state (bound conformation) of the glutamate transporter homologue gltph
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 47-320 274 1-46 337-410 321-336 46 74 slipknot
Chain Sequence
YIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLCMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVATFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLCMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTE
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1 46-310 265 1-45 345-410 311-344 45 66 slipknot
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2.1 30-358 329 1-3, 368-410 4-29, 359-367 3 43 slipknot
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1.1 52-323 272 1-46, 331-410 47-51, 324-330 46 80 slipknot
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1.1 58-314 257 1-48, 327-410 49-57, 315-326 48 84 slipknot
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1.1 58-326 269 1-51, 328-410 52-57, 327-327 51 83 slipknot
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1.1 61-328 268 1-48, 342-410 49-60, 329-341 48 69 slipknot
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1.1 59-361 303 1-49, 368-410 50-58, 362-367 49 43 slipknot
publication title Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
pubmed doi rcsb
structure length 410
molecule tags Transport protein
source organism Pyrococcus horikoshii
sequence length 410
molecule keywords GltPh
ec nomenclature
pdb deposition date 2014-03-24
KnotProt deposition date 2014-08-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00375 SDF Sodium:dicarboxylate symporter family
Image from the rcsb pdb (www.rcsb.org)
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