4P6HC

Tl+-bound inward-facing state (bound conformation) of the glutamate transporter homologue gltph
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 48-322 275 1-47 338-410 323-337 47 73 slipknot
Chain Sequence
YIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLCMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVATFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLCMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTE
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1 43-311 269 1-42 345-410 312-344 42 66 slipknot
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2.1 39-358 320 1-38 370-410 359-369 38 41 slipknot
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2.1 52-318 267 1-43, 328-410 44-51, 319-327 43 83 slipknot
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1.1 60-326 267 1-44, 343-410 45-59, 327-342 44 68 slipknot
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1.1 57-315 259 1-49, 324-410 50-56, 316-323 49 87 slipknot
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1.1 59-315 257 1-56, 324-410 57-58, 316-323 56 87 slipknot
publication title Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
pubmed doi rcsb
structure length 410
molecule tags Transport protein
source organism Pyrococcus horikoshii
sequence length 410
molecule keywords GltPh
ec nomenclature
pdb deposition date 2014-03-24
KnotProt deposition date 2014-08-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00375 SDF Sodium:dicarboxylate symporter family
Image from the rcsb pdb (www.rcsb.org)
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