4UELA

Uch-l5 in complex with ubiquitin-propargyl bound to the rpn13 deubad domain
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 52 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Knot K -52 -31 -31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
-31 5-161 157 1-4 215-315 162-214 4 101 slipknot
view details
-52 5-218 214 1-4, 219-315 4 97 knot
Chain Sequence
GEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDT------EDAFHFVSYVPVNGRLYELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEENSMLSA-------IQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQN
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
4.4m 9-214 206 1-8, 215-302 8 88 knot
view details
2.1m 7-161 155 1-6 170-302 162-169 6 133 slipknot
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1.1m 6-170 165 1-5 177-302 171-176 5 126 slipknot
view details
2.1m 8-176 169 1-7 208-302 177-207 7 95 slipknot
view details
2.1m 7-156 150 1-2, 161-302 3-6, 157-160 2 142 slipknot
missing residues 149-154, 241-247
publication title Mechanism of Uch-L5 Activation and Inhibition by Deubad Domains in Rpn13 and Ino80G.
pubmed doi rcsb
structure length 302
molecule tags Hydrolase
source organism Homo sapiens
sequence length 315
total genus Genus: 102
molecule keywords UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5
ec nomenclature
pdb deposition date 2014-12-18
KnotProt deposition date 2015-03-04
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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