4UEMA

Uch-l5 in complex with the rpn13 deubad domain
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 52 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Knot K -52 -31 -31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
-31 4-160 157 1-3 214-309 161-213 3 96 slipknot
view details
-52 4-218 215 1-3, 219-309 3 91 knot
Chain Sequence
EWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFE-------------HFVSYVPVNGRLYELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKRFNLMAIVSDRKM------IYEQKIAELQRQLAESMLSAIQSEVAKNQMLIEE---------EVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKA
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
4.4m 6-199 194 1-5, 200-281 5 82 knot
view details
3.1m 2-150 149 1-1 158-281 151-157 1 124 slipknot
view details
3.1m 4-167 164 1-3 188-281 168-187 3 94 slipknot
view details
3.1m 4-189 186 1-3 194-281 190-193 3 88 slipknot
missing residues 145-157, 205-210, 239-247
publication title Mechanism of Uch-L5 Activation and Inhibition by Deubad Domains in Rpn13 and Ino80G.
pubmed doi rcsb
structure length 281
molecule tags Hydrolase
source organism Homo sapiens
sequence length 309
total genus Genus: 86
molecule keywords UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5
ec nomenclature
pdb deposition date 2014-12-18
KnotProt deposition date 2015-03-04
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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