4UF5A

Crystal structure of uch-l5 in complex with inhibitory fragment of ino80g
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 52 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Knot K -52 -31 -31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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-31 7-160 154 1-6 217-315 161-216 6 99 slipknot
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-52 7-218 212 1-6, 219-315 6 97 knot
Chain Sequence
GEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQ------------EDAFHFVSYVPVNGRLYELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLASMLSAIQSEVAK----------NQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQN
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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5.2m 6-257 252 1-5, 258-293 5 36 knot
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2.1m 6-146 141 1-5 153-293 147-152 5 141 slipknot
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3.1m 6-152 147 1-5 159-293 153-158 5 135 slipknot
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3.1m 8-169 162 1-7 203-293 170-202 7 91 slipknot
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5.2m 6-208 203 1-5 253-293 209-252 5 41 slipknot
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5.2m 9-208 200 209-293 1-2 3-8 2 84 slipknot
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4.4m 10-224 215 225-293 1-8 9-9 8 68 slipknot
missing residues 143-154, 239-248
publication title Mechanism of Uch-L5 Activation and Inhibition by Deubad Domains in Rpn13 and Ino80G.
pubmed doi rcsb
structure length 293
molecule tags Hydrolase
source organism Homo sapiens
sequence length 315
total genus Genus: 90
molecule keywords UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5
ec nomenclature
pdb deposition date 2014-12-23
KnotProt deposition date 2015-03-04
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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