4UX8C

Ret recognition of gdnf-gfralpha1 ligand by a composite binding site promotes membrane-proximal self-association
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 94
Knot K +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 86-267 182 1-85, 268-319 85 52 knot
Chain Sequence
DRLDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLTSGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQS-----------------------------------KGNNCLDAAKACNLDDTCKKYRSAYITPCTTSMSNEVCNRRKCHKALRQFFDKVPAKHSYGMLFCSCRDIACTERRRQTIVPVCSYEERERPNCLSLQDSCKTNYICRSRLADFFTNCQPESRSVSNCLKENYADCLLAYSGLIGTVMTPNYVDSSSLSVAPWCDCSNSGNDLEDCLKFLNFFKDNTCLKNAIQAFGNG
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1 86-225 140 1-85 238-284 226-237 85 47 slipknot
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3.1 86-248 163 1-85 274-284 249-273 85 11 slipknot
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2.1 37-237 201 1-24, 246-284 25-36, 238-245 24 39 slipknot
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3.1 86-237 152 1-36, 246-284 37-85, 238-245 36 39 slipknot
How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling