4WLRA

Crystal structure of much37-hrpn13 ctd complex
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 52 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Knot K -52 -31 -31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
-31 6-160 155 1-5 217-313 161-216 5 97 slipknot
view details
-52 5-219 215 1-4, 220-313 4 94 knot
Chain Sequence
GEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPESFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLETIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFE----------DAFHFVSYVPVNGRLYELDGLREGPIDLGACNQDDWITAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEPTVLSAIQSEV-------ARNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEK
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
4.4m 9-210 202 1-8, 211-296 8 86 knot
view details
3.1m 6-152 147 1-5 162-296 153-161 5 135 slipknot
view details
2.1m 4-161 158 1-3 165-296 162-164 3 132 slipknot
view details
1.1m 6-167 162 1-5 172-296 168-171 5 125 slipknot
view details
3.1m 4-185 182 1-3 205-296 186-204 3 92 slipknot
view details
5.2m 4-209 206 1-3 250-296 210-249 3 47 slipknot
missing residues 146-155, 242-248
publication title Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase.
doi rcsb
structure length 296
molecule tags Protein binding
source organism Mus musculus
sequence length 313
total genus Genus: 100
molecule keywords Ubiquitin carboxyl-terminal hydrolase isozyme L5
ec nomenclature
pdb deposition date 2014-10-08
KnotProt deposition date 2015-03-05
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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