4XNXA

X-ray structure of drosophila dopamine transporter in complex with reboxetine
Slipknot S +31 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 39-268 230 269-536 1-18 19-38 18 267 slipknot
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41 15-297 283 1-14 355-536 298-354 14 182 slipknot
Chain Sequence
DERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLAVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFEGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLATLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFTILTTPWRDQQ
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 12-293 282 1-11 306-536 294-305 11 231 slipknot
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3.2 12-305 294 1-11 320-536 306-319 11 217 slipknot
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4.1 8-328 321 1-7 341-536 329-340 7 196 slipknot
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3.2 12-339 328 1-11 355-536 340-354 11 182 slipknot
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3.2 21-332 312 1-7, 348-536 8-20, 333-347 7 189 slipknot
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3.2 21-347 327 1-11, 351-536 12-20, 348-350 11 186 slipknot
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4.1 21-350 330 1-11, 355-536 12-20, 351-354 11 182 slipknot
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1.1 27-283 257 1-17, 293-536 18-26, 284-292 17 244 slipknot
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2.1 43-361 319 1-17, 396-536 18-42, 362-395 17 141 slipknot
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2.1 44-419 376 420-536 1-17 18-43 17 116 slipknot
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1.1 37-251 215 1-20, 265-536 21-36, 252-264 20 272 slipknot
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2.1 35-264 230 1-21, 271-536 22-34, 265-270 21 266 slipknot
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2.1 35-270 236 1-21, 281-536 22-34, 271-280 21 256 slipknot
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2.1 43-278 236 1-28, 293-536 29-42, 279-292 28 244 slipknot
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1.1 43-292 250 1-28, 301-536 29-42, 293-300 28 236 slipknot
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2.1 39-403 365 1-31, 410-536 32-38, 404-409 31 127 slipknot
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1.1 40-265 226 1-34, 271-536 35-39, 266-270 34 266 slipknot
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2.1 42-268 227 1-35, 279-536 36-41, 269-278 35 258 slipknot
publication title X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetine.
pubmed doi rcsb
structure length 536
molecule tags Transport protein/inhibitor
source organism Drosophila melanogaster
sequence length 536
total genus Genus: 207
molecule keywords Transporter
ec nomenclature
pdb deposition date 2015-01-16
KnotProt deposition date 2015-11-11
Image from the rcsb pdb (www.rcsb.org)
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