4XP5A

X-ray structure of drosophila dopamine transporter bound to cocaine analogue-rti55
Slipknot S +31 41
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 39-268 230 269-534 1-22 23-38 22 265 slipknot
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41 16-297 282 1-15 355-534 298-354 15 180 slipknot
Chain Sequence
DERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLAVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFEGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLATLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFTILTTPWRD
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 14-293 280 1-13 307-534 294-306 13 228 slipknot
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4.1 11-306 296 1-10 314-534 307-313 10 221 slipknot
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4.1 12-306 295 1-11 329-534 307-328 11 206 slipknot
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4.1 5-335 331 1-4 343-534 336-342 4 192 slipknot
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3.2 21-337 317 1-20 356-534 338-355 20 179 slipknot
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3.2 11-333 323 1-4, 338-534 5-10, 334-337 4 197 slipknot
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4.1 13-314 302 1-11, 319-534 12-12, 315-318 11 216 slipknot
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4.1 19-308 290 1-13, 315-534 14-18, 309-314 13 220 slipknot
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3.2m 20-303 284 1-14, 309-534 15-19, 304-308 14 226 slipknot
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2.1 42-363 322 1-18, 399-534 19-41, 364-398 18 136 slipknot
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2.1 44-470 427 471-534 1-18 19-43 18 63 slipknot
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2.1 27-283 257 1-21, 289-534 22-26, 284-288 21 246 slipknot
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2.1 27-288 262 1-21, 290-534 22-26, 289-289 21 245 slipknot
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1.1 43-282 240 1-25, 302-534 26-42, 283-301 25 233 slipknot
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1.1 40-251 212 1-26, 265-534 27-39, 252-264 26 270 slipknot
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2.1 39-269 231 1-27, 283-534 28-38, 270-282 27 252 slipknot
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2.1 39-399 361 1-31, 415-534 32-38, 400-414 31 120 slipknot
publication title Neurotransmitter and psychostimulant recognition by the dopamine transporter
rcsb
structure length 534
molecule tags Transport protein/inhibitor
source organism Drosophila melanogaster
sequence length 534
total genus Genus: 194
molecule keywords Dopamine transporter, isoform B
ec nomenclature
pdb deposition date 2015-01-16
KnotProt deposition date 2015-05-07
Image from the rcsb pdb (www.rcsb.org)
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