4XPBA

X-ray structure of drosophila dopamine transporter with subsiteb mutations (d121g/s426m) bound to cocaine
Slipknot S +31 41 +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 39-266 228 267-532 1-21 22-38 21 265 slipknot
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41 15-295 281 1-14 353-532 296-352 14 180 slipknot
Chain Sequence
DERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLAVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVGFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFESQGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLATLGLDSSFGGMEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFTILTTPWRD
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 13-291 279 1-12 303-532 292-302 12 230 slipknot
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4.1 11-302 292 1-10 317-532 303-316 10 216 slipknot
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4.1 6-328 323 1-5 345-532 329-344 5 188 slipknot
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4.1 20-335 316 1-19 347-532 336-346 19 186 slipknot
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4.1 20-346 327 1-19 353-532 347-352 19 180 slipknot
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3.2 9-352 344 1-8 354-532 353-353 8 179 slipknot
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3.2 20-353 334 1-1, 356-532 2-19, 354-355 1 177 slipknot
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3.2 19-325 307 1-11, 334-532 12-18, 326-333 11 199 slipknot
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3.2 19-300 282 1-13, 309-532 14-18, 301-308 13 224 slipknot
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3.1 24-267 244 1-17, 277-532 18-23, 268-276 17 256 slipknot
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2.1 39-358 320 1-17, 396-532 18-38, 359-395 17 137 slipknot
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2.1 43-410 368 1-17, 483-532 18-42, 411-482 17 50 slipknot
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2.1 33-262 230 1-21, 278-532 22-32, 263-277 21 255 slipknot
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1.1 30-248 219 1-22, 259-532 23-29, 249-258 22 274 slipknot
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1.1 40-247 208 1-27, 262-532 28-39, 248-261 27 271 slipknot
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1.1 40-261 222 1-27, 266-532 28-39, 262-265 27 267 slipknot
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2.1 43-281 239 1-27, 299-532 28-42, 282-298 27 234 slipknot
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2.1 41-265 225 1-35, 274-532 36-40, 266-273 35 259 slipknot
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2.1 41-273 233 1-35, 277-532 36-40, 274-276 35 256 slipknot
publication title Neurotransmitter and psychostimulant recognition by the dopamine transporter.
pubmed doi rcsb
structure length 532
molecule tags Tranport protein/inhibitor
source organism Drosophila melanogaster
sequence length 532
total genus Genus: 199
molecule keywords Transporter
ec nomenclature
pdb deposition date 2015-01-16
KnotProt deposition date 2015-11-11
Image from the rcsb pdb (www.rcsb.org)
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