4XPGA

X-ray structure of drosophila dopamine transporter with subsiteb mutations (d121g/s426m) bound to beta-cft or win35428
Slipknot S +31 41
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 39-267 229 268-533 1-21 22-38 21 265 slipknot
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41 18-295 278 1-17 353-533 296-352 17 181 slipknot
Chain Sequence
DERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLAVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVGFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFESQGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAALLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWADAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLATLGLDSSFGGMEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYLLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFTILTTPWRDQ
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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4.1 11-298 288 1-10 316-533 299-315 10 218 slipknot
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4.1 7-317 311 1-6 339-533 318-338 6 195 slipknot
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4.1 15-335 321 1-14 351-533 336-350 14 183 slipknot
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3.2 15-350 336 1-14 354-533 351-353 14 180 slipknot
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4.1 13-334 322 1-6, 336-533 7-12, 335-335 6 198 slipknot
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2.1 44-416 373 417-533 1-17 18-43 17 116 slipknot
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2.1 43-357 315 1-18, 397-533 19-42, 358-396 18 137 slipknot
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2.1 33-262 230 1-19, 275-533 20-32, 263-274 19 259 slipknot
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1.1 30-280 251 1-22, 291-533 23-29, 281-290 22 243 slipknot
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1.1 39-248 210 1-27, 259-533 28-38, 249-258 27 275 slipknot
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1.1 43-278 236 1-28, 299-533 29-42, 279-298 28 235 slipknot
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2.1 38-259 222 1-32, 267-533 33-37, 260-266 32 267 slipknot
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2.1 38-398 361 1-32, 406-533 33-37, 399-405 32 128 slipknot
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2.1 42-268 227 1-35, 278-533 36-41, 269-277 35 256 slipknot
publication title Structural basis for neurotransmitter and psycho stimulant recognition by the Drosophila dopamine transporter
rcsb
structure length 533
molecule tags Transport protein/inhibitor
source organism Drosophila melanogaster
sequence length 533
total genus Genus: 194
molecule keywords Dopamine transporter
ec nomenclature
pdb deposition date 2015-01-16
KnotProt deposition date 2015-05-07
Image from the rcsb pdb (www.rcsb.org)
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