4XPHA

X-ray structure of drosophila dopamine transporter with subsiteb mutations (d121g/s426m) bound to 3,4dichlorophenethylamine
Slipknot S +31 41
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 38-268 231 269-534 1-21 22-37 21 265 slipknot
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41 17-297 281 1-16 355-534 298-354 16 180 slipknot
Chain Sequence
DERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLAVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVGFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFEGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLATLGLDSSFGGMEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFTILTTPWRD
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 15-293 279 1-14 306-534 294-305 14 229 slipknot
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4.1 11-305 295 1-10 330-534 306-329 10 205 slipknot
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4.1 7-330 324 1-6 342-534 331-341 6 193 slipknot
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4.1 21-335 315 1-20 353-534 336-352 20 182 slipknot
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3.2 20-352 333 1-19 356-534 353-355 19 179 slipknot
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3.2 12-305 294 1-10, 311-534 11-11, 306-310 10 224 slipknot
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4.1 13-331 319 1-6, 336-534 7-12, 332-335 6 199 slipknot
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2.1 35-263 229 1-17, 276-534 18-34, 264-275 17 259 slipknot
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2.1 43-425 383 426-534 1-17 18-42 17 108 slipknot
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2.1 42-360 319 1-18, 397-534 19-41, 361-396 18 138 slipknot
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1.1 39-251 213 1-23, 262-534 24-38, 252-261 23 273 slipknot
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1.1 39-261 223 1-23, 265-534 24-38, 262-264 23 270 slipknot
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1.1 40-283 244 1-24, 301-534 25-39, 284-300 24 234 slipknot
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2.1 40-411 372 1-33, 417-534 34-39, 412-416 33 118 slipknot
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2.1 42-269 228 1-35, 283-534 36-41, 270-282 35 252 slipknot
publication title Structural basis for neurotransmitter and psychostimulant recognition by the Drosophila dopamine transporter
rcsb
structure length 534
molecule tags Protein transport/inhibitor
source organism Drosophila melanogaster
sequence length 534
total genus Genus: 206
molecule keywords Transporter
ec nomenclature
pdb deposition date 2015-01-17
KnotProt deposition date 2015-05-07
Image from the rcsb pdb (www.rcsb.org)
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