4YNP | KnotProt

Cysteine knot

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Help Cysteine knot data interpretation Full screen

				Loop	Piercing
view details				2117-c-2122-b-2128-c-2128	2117-b-2122

Chain Sequence

SYKKIRSNVYVDVKPLSC-------------------VDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHMFNVEKQQLCKCGFEKCRGII

sequence length	212
structure length	193
publication title	Two Loops Undergoing Concerted Dynamics Regulate the Activity of the ASH1L Histone Methyltransferase. pubmed doi rcsb
molecule tags	Transferase
molecule keywords	Histone-lysine N-methyltransferase ASH1L
source organism	Homo sapiens
missing residues	18-36
ec nomenclature	ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date	2015-03-10

Image from the rcsb pdb (www.rcsb.org)

None 3OPEA 4YNMA 4YPAA 4YPEA 4YPUA 6AGOA 6INEA 6WZWA 6X0PA
similar chains in the KnotProt database (40% sequence similarity)

None
similar chains in the pdb database (40% sequence similarity)

#similar chains in the KnotProt database (40% sequence similarity)

#similar chains, but unknotted
6X0P A; 
#similar chains in the pdb database (40% sequence similarity)

4YNPB

Cysteine knot

Chain Sequence