5A1IA

The structure of humab mat2a in complex with same, adenosine, methionine and ppnp.
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 16-270 255 1-15, 271-381 15 111 knot
Chain Sequence
EGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1 21-285 265 1-2, 350-381 3-20, 286-349 2 32 slipknot
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2.1 19-349 331 1-4, 351-381 5-18, 350-350 4 31 slipknot
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2.1 18-274 257 1-3, 286-381 4-17, 275-285 3 96 slipknot
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2.1 20-277 258 1-17, 286-381 18-19, 278-285 17 96 slipknot
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1.1 20-363 344 1-5, 380-381 6-19, 364-379 5 2 slipknot
sequence length 381
structure length 381
publication title Crystallography Captures Catalytic Steps in Human Methionine Adenosyltransferase Enzymes.
pubmed doi rcsb
molecule tags Transferase
molecule keywords S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2
source organism Homo sapiens
total genus Genus: 142
ec nomenclature
pdb deposition date 2015-04-30
KnotProt deposition date 2016-03-10
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the pdb database (?% sequence similarity)

 
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