5EA3F

Crystal structure of inhibitor jnj-2408068 in complex with prefusion rsv f glycoprotein
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 27-264 238 1-26 271-480 265-270 26 210 slipknot
Chain Sequence
NITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIK---------KVKLIKQELDKYKNAVTELQLLMFLGFLLGVG---------------------------------------SAIASGVAVCKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTFKVLDLKNYIDKQLLETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMP-------------ITNDQKKLMSNNVQIVRQQSYSIMCIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFI
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 31-261 231 1-30 275-480 262-274 30 206 slipknot
sequence length 480
structure length 419
publication title Molecular mechanism of respiratory syncytial virus fusion inhibitors.
pubmed doi rcsb
molecule tags Cell invasion/inhibitor
molecule keywords Fusion glycoprotein F0
source organism Human respiratory syncytial virus a (strain a2)
missing residues 40-48, 72-110, 179-191
total genus Genus: 122
ec nomenclature
pdb deposition date 2015-10-15
KnotProt deposition date 2018-09-12
Image from the rcsb pdb (www.rcsb.org)
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