5EA6F

Crystal structure of inhibitor bta-9881 in complex with prefusion rsv f glycoprotein
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Slipknot S +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 28-265 238 1-27 272-480 266-271 27 209 slipknot
Chain Sequence
NITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIK--------AKVKLIKQELDKYKNAVTELQLLMQFLGFLLGV--------------------------------------GSAIASGVAVCKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTFKVLDLKNYIDKQLLIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLIN------------DMPITNDQKKLMSNNVQIVRQQSYSIMCIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFI
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1 28-266 239 1-27 270-480 267-269 27 211 slipknot
sequence length 480
structure length 422
publication title Molecular mechanism of respiratory syncytial virus fusion inhibitors.
pubmed doi rcsb
molecule tags Cell invasion/inhibitor
molecule keywords Fusion glycoprotein F0
source organism Human respiratory syncytial virus a (strain a2)
missing residues 40-47, 73-110, 179-190
total genus Genus: 137
ec nomenclature
pdb deposition date 2015-10-15
KnotProt deposition date 2018-09-12
Image from the rcsb pdb (www.rcsb.org)
5EA4F 5EA5F 5EA6F 5KWWF 5UDCA 6DC3F 6DC5A 5EA7F
similar chains in the KnotProt database (40% sequence similarity)
6VKCF
similar chains in the pdb database (40% sequence similarity)

 
#similar chains in the KnotProt database (40% sequence similarity)
5EA4 F; 5EA5 F; 5EA6 F; 5KWW F; 5UDC A; 6DC3 F; 6DC5 A; 
#similar chains, but unknotted
5EA7 F; 
#similar chains in the pdb database (40% sequence similarity)
6VKC F; 

KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling