5HWYA

Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger ncx_mj soaked with 10 mm na+ and zero ca2+
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 44-230 187 1-43, 231-300 43 70 knot
Chain Sequence
MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIEENNDKNNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLR
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1 21-248 228 1-20, 249-300 20 52 knot
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3.1 18-236 219 1-4, 249-300 5-17, 237-248 4 52 slipknot
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2.1 28-248 221 1-20, 281-300 21-27, 249-280 20 20 slipknot
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3.1 28-280 253 1-20, 285-300 21-27, 281-284 20 16 slipknot
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3.1 28-284 257 285-300 1-20 21-27 20 15 slipknot
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2.1 38-244 207 245-300 1-17 18-37 17 55 slipknot
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2.1 40-239 200 1-17, 269-300 18-39, 240-268 17 32 slipknot
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2.1 40-268 229 269-300 1-37 38-39 37 31 slipknot
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2.1 44-244 201 245-300 1-39 40-43 39 55 slipknot
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2.1 47-241 195 1-39, 269-300 40-46, 242-268 39 32 slipknot
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2.1 47-268 222 269-300 1-43 44-46 43 31 slipknot
publication title Mechanism of extracellular ion exchange and binding-site occlusion in the sodium-calcium exchanger
doi rcsb
structure length 300
molecule tags Membrane protein
source organism Methanocaldococcus jannaschii (strain atcc 43067 / dsm 2661 / jal-1 / jcm 10045
sequence length 300
total genus Genus: 133
molecule keywords Uncharacterized membrane protein MJ0091
ec nomenclature
pdb deposition date 2016-01-29
KnotProt deposition date 2016-05-22
Image from the rcsb pdb (www.rcsb.org)
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