5IF5A

Crystal structure of polymerase acid protein (pa) from influenza a virus, wilson-smith/1933 (h1n1) bound to ebsi-39 (2,3-dichlorophenyl)methanol
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 140
Slipknot S -31

  Help Knotting data interpretation Full screen
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
-31 18-288 271 1-15, 293-449 16-17, 289-292 15 157 slipknot
Chain Sequence
PRPLRLPDGPPCSQRSKFLLMDALKLSIEDP-----GIPLYDAIKCMRTFFGWKEPNVVKPHEKGINPNYLLSWKQVLAELQDIENEEKIPRTKNMKKTSQLKWALGEELRSL--------------------------ASWIQNEFNKACELTDSSWIELDEIGEDAAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEVGDMLLRSAIGHVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKESPKGVEEGSIGKVCRTLLAKSVFNSLYASP-------QLEGFSAESRKLLLIVQALRDNLEFDLGGLYEAIEECLINDPWVLLNASWFNSFLTH
Whole chain analysis

  Help Knotoid data interpretation Full screen
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


  Help Knotoid subchains data interpretation Full screen
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1m 23-280 258 1-11, 298-449 12-22, 281-297 11 152 slipknot
view details
2.1m 20-262 243 1-12, 274-449 13-19, 263-273 12 176 slipknot
sequence length 449
structure length 408
publication title Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA
rcsb
molecule tags Viral protein
molecule keywords Polymerase acidic protein
source organism Influenza a virus (strain a/wilson-smith/1933 h1n1)
missing residues 32-36, 109-134, 352-358, 414-416
total genus Genus: 140
ec nomenclature
pdb deposition date 2016-02-25
KnotProt deposition date 2018-09-16
Image from the rcsb pdb (www.rcsb.org)
...loading similar chains, please wait...
similar chains in the KnotProt database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the KnotProt database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling