5JAEA

Leut in the outward-oriented, na+-free return state, p21 form at ph 6.5
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
  • Chain breaks within knot 41 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 191
Slipknot S +31 41 +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 38-262 225 263-509 1-20 21-37 20 246 slipknot
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41 14-293 280 1-13 351-509 294-350 13 159 slipknot
Chain Sequence
KREHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLVGIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVVAIYYVYIESWTLGFAIKFLVGLVPEPP--ATDPDSILRPFKEFLYSYIGVPKGDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILAVFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFTLSLGFGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFFGVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSSIAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFWAGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYITPAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAERRRNHES
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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3.2 13-287 275 1-12 301-507 288-300 12 207 slipknot
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4.1 6-312 307 1-5 322-507 313-321 5 186 slipknot
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4.1 7-327 321 1-6 333-507 328-332 6 175 slipknot
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3.2m 13-332 320 1-12 350-507 333-349 12 158 slipknot
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3.2 11-302 292 1-2, 311-507 3-10, 303-310 2 197 slipknot
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4.1 11-310 300 1-3, 314-507 4-10, 311-313 3 194 slipknot
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2.1 42-355 314 1-17, 399-507 18-41, 356-398 17 109 slipknot
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2.1 42-410 369 1-18, 490-507 19-41, 411-489 18 18 slipknot
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2.1 34-258 225 1-19, 274-507 20-33, 259-273 19 234 slipknot
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1.1 40-244 205 1-23, 256-507 24-39, 245-255 23 252 slipknot
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1.1 42-273 232 1-26, 292-507 27-41, 274-291 26 216 slipknot
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2.1 39-399 361 1-32, 407-507 33-38, 400-406 32 101 slipknot
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1.1 43-274 232 1-41, 291-507 42-42, 275-290 41 217 slipknot
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2.1 42-261 220 1-34, 270-507 35-41, 262-269 34 238 slipknot
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2.1 42-269 228 1-34, 274-507 35-41, 270-273 34 234 slipknot
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2.1 43-265 223 1-41, 273-507 42-42, 266-272 41 235 slipknot
sequence length 509
structure length 507
publication title A conserved leucine occupies the empty substrate site of LeuT in the Na(+)-free return state.
pubmed doi rcsb
molecule tags Membrane protein
molecule keywords Transporter
source organism Aquifex aeolicus (strain vf5)
missing residues 129-130
total genus Genus: 191
ec nomenclature
pdb deposition date 2016-04-12
KnotProt deposition date 2016-06-03
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling