5JDQA

Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger ncx_mj soaked with 100 mm na+ and 10mm sr2+
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 127
Knot K +31

  Help Knotting data interpretation Full screen
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
+31 41-229 189 1-40, 230-301 40 72 knot
Chain Sequence
MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIE-----NNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRM
Note, that the numbers in the matrix denote the consecutive residues in the loop, not the index of amino acids in the chain!
Knot K 203x +31

  Help Knotting data interpretation Full screen
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
+ 31 42-228 187 1-41, 229-297 41 69 knot
Fingerprint Knot forming loop Loop type
K +31 Met1 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Glu54 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Glu213 <->
Bridging ionNa402
<-> Glu54		 ion-based
K +31
Chain closureMet1 <-> Met301
... Ser210 <->
Bridging ionNa403
<-> Glu54 ... Thr209 <->
Bridging ionNa402
<-> Thr50 ... Met1		 probabilistic
K +31 Ala47 <->
Bridging ionNa401
<-> Ser236 ... Glu213 <->
Bridging ionNa401
<-> Thr50 ... Ala47		 ion-based
K +31 Thr50 <->
Bridging ionNa402
<-> Glu54 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Met1 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ser77 <->
Bridging ionNa403
<-> Ala206 ... Glu213 <->
Bridging ionNa401
<-> Ser236 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Thr50 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Ala47 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Glu54 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Glu213 <->
Bridging ionNa402
<-> Glu54		 ion-based
K +31 Glu54 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Glu213 <->
Bridging ionNa402
<-> Glu54		 ion-based
K +31 Ala206 ... Ser210 <->
Bridging ionNa403
<-> Ala206		 ion-based
K +31 Met1 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31
Chain closureMet1 <-> Met301
... Ser210 <->
Bridging ionNa403
<-> Glu54 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Thr50 ... Met1		 probabilistic
K +31 Met1 ... Glu54 <->
Bridging ionNa403
<-> Ser210 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Ala47 ... Thr50 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Glu54 ... Ser51 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 <->
Bridging ionNa401
<-> Ser236 ... Glu213 <->
Bridging ionNa402
<-> Glu54 ... Ala47		 ion-based
K +31 Ala47 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 <->
Bridging ionNa401
<-> Ser236 ... Ser210 <->
Bridging ionNa403
<-> Glu54 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Thr50 ... Ala47		 ion-based
K +31 Thr50 <->
Bridging ionNa401
<-> Ser236 ... Glu213 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Thr50 <->
Bridging ionNa401
<-> Ser236 ... Glu213 <->
Bridging ionNa402
<-> Glu54 ... Thr50		 ion-based
K +31 Thr50 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Thr50 ... Ser77 <->
Bridging ionNa403
<-> Ala206 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Thr50 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Met1 ... Glu54 <->
Bridging ionNa403
<-> Ala206 ... Glu213 <->
Bridging ionNa401
<-> Ser236 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31
Chain closureMet1 <-> Met301
... Ser236 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Ser77 ... Thr209 <->
Bridging ionNa402
<-> Thr50 ... Met1		 probabilistic
K +31
Chain closureMet1 <-> Met301
... Ser236 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Ser77 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Glu54 ... Met1		 probabilistic
K +31
Chain closureMet1 <-> Met301
... Ser236 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Glu54 ... Thr209 <->
Bridging ionNa402
<-> Thr50 ... Met1		 probabilistic
K +31 Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Glu213 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Thr50 <->
Bridging ionNa402
<-> Glu54 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Ser236 <->
Bridging ionNa401
<-> Ser51 ... Thr50		 ion-based
K +31 Ala47 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Thr50 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Ala47 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Glu213 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Ser77 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Thr50 ... Ala47		 ion-based
K +31 Ala47 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Glu54 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Thr50 ... Ala47		 ion-based
K +31 Thr50 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Thr50 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Glu213 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Thr50 ... Ser51 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Thr50		 ion-based
K +31 Ala47 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Thr50 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Thr50 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Ala47 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Glu213 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Thr50 ... Ala47		 ion-based
K +31 Met1 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Glu213 <->
Bridging ionNa401
<-> Ser236 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Glu54		 ion-based
K +31 Met1 ... Thr50 <->
Bridging ionNa402
<-> Thr209 ... Asp121 <->
Bridging ionSr404
<-> Ile118 ... Ser51 <->
Bridging ionNa401
<-> Glu213 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Ala47 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Thr50 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Ala47 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Glu213 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Met1 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Glu213 <->
Bridging ionNa401
<-> Ser236 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Thr50 <->
Bridging ionNa402
<-> Thr209 ... Gly122 <->
Bridging ionSr404
<-> Ile118 ... Ser77 <->
Bridging ionNa403
<-> Ser210 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Thr50 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Ala206 ... Gly122 <->
Bridging ionSr404
<-> Ile118 ... Ser51 <->
Bridging ionNa401
<-> Ser236 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Glu54 <->
Bridging ionNa402
<-> Glu213 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Glu54 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Thr209 <->
Bridging ionNa402
<-> Glu54		 ion-based
K +31 Glu54 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Thr209 <->
Bridging ionNa402
<-> Glu54		 ion-based
K +31 Met1 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Glu54 <->
Bridging ionNa403
<-> Ser210 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Thr50 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Glu54 ... Thr50		 ion-based
K +31 Glu54 <->
Bridging ionNa402
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Glu54		 ion-based
K +31 Ala47 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 ... Ser77 <->
Bridging ionNa403
<-> Ala206 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 <->
Bridging ionNa401
<-> Ser236 ... Ala206 <->
Bridging ionNa403
<-> Ser77 ... Glu54 <->
Bridging ionNa402
<-> Thr50 ... Ala47		 ion-based
K +31 Ala47 <->
Bridging ionNa401
<-> Ser236 ... Ser210 <->
Bridging ionNa403
<-> Glu54 ... Ala47		 ion-based
K +31 Ala47 <->
Bridging ionNa401
<-> Ser236 ... Glu213 <->
Bridging ionNa402
<-> Thr209 ... Ser210 <->
Bridging ionNa403
<-> Glu54 ... Ala47		 ion-based
K +31 Thr50 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Thr50 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Thr50 <->
Bridging ionNa401
<-> Ser236 ... Glu213 <->
Bridging ionNa402
<-> Thr209 ... Ala206 <->
Bridging ionNa403
<-> Ser77 ... Thr50		 ion-based
K +31 Thr50 <->
Bridging ionNa401
<-> Ser236 ... Glu213 <->
Bridging ionNa402
<-> Thr209 ... Ala206 <->
Bridging ionNa403
<-> Glu54 ... Thr50		 ion-based
K +31 Thr50 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31
Chain closureMet1 <-> Met301
... Ser236 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Ser77 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Thr50 ... Met1		 probabilistic
K +31 Met1 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ser77 <->
Bridging ionNa403
<-> Ser210 ... Glu213 <->
Bridging ionNa401
<-> Ser236 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31
Chain closureMet1 <-> Met301
... Ser236 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Glu54 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Thr50 ... Met1		 probabilistic
K +31 Met1 ... Glu54 <->
Bridging ionNa403
<-> Ser210 ... Glu213 <->
Bridging ionNa401
<-> Ser236 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Thr50 <->
Bridging ionNa402
<-> Glu54 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Glu213 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Thr50 <->
Bridging ionNa402
<-> Glu54 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Glu213 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ser77 <->
Bridging ionNa403
<-> Thr209 ... Glu213 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Met1 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Thr50 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Glu213 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31
Chain closureMet1 <-> Met301
... Ser236 <->
Bridging ionNa401
<-> Ser51 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Glu213 <->
Bridging ionNa401
<-> Thr50 ... Met1		 probabilistic
K +31
Chain closureMet1 <-> Met301
... Ser236 <->
Bridging ionNa401
<-> Ser51 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Glu213 <->
Bridging ionNa401
<-> Thr50 ... Met1		 probabilistic
K +31 Ser51 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Ser236 <->
Bridging ionNa401
<-> Ser51		 ion-based
K +31 Thr50 <->
Bridging ionNa402
<-> Glu54 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Ser236 <->
Bridging ionNa401
<-> Ser51 ... Thr50		 ion-based
K +31 Ala47 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Glu213 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Ser77 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Glu54 ... Ala47		 ion-based
K +31 Ala47 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Glu213 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Thr50 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Thr50 <->
Bridging ionNa402
<-> Glu54 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Thr50 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Met1 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Glu213 <->
Bridging ionNa401
<-> Ser236 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Thr50 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Thr50		 ion-based
K +31 Ile118 <->
Bridging ionSr404
<-> Asp127 ... Ile118		 ion-based
K +31 Ala47 <->
Bridging ionNa401
<-> Ser51 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Glu213 <->
Bridging ionNa401
<-> Thr50 ... Ala47		 ion-based
K +31 Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Glu213 <->
Bridging ionNa402
<-> Glu54		 ion-based
K +31 Ser51 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Ser236 <->
Bridging ionNa401
<-> Ser51		 ion-based
K +31 Ser51 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ... Ser236 <->
Bridging ionNa401
<-> Ser51		 ion-based
K +31 Ser51 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Glu54 ... Ser51		 ion-based
K +31 Thr50 ... Ser51 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Thr50		 ion-based
K +31
Chain closureMet1 <-> Met301
... Glu213 <->
Bridging ionNa401
<-> Ser51 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Thr50 ... Met1		 probabilistic
K +31 Ala47 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Thr50 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Thr50 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Ala47 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Glu213 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Glu213 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Glu213 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Thr50 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Glu213 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Thr50 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Glu54 ... Thr50		 ion-based
K +31 Met1 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Thr50 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Thr209 <->
Bridging ionNa402
<-> Thr50		 ion-based
K +31 Met1 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Ser51 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Glu213 <->
Bridging ionNa401
<-> Ser51		 ion-based
K +31 Ser51 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Glu213 <->
Bridging ionNa401
<-> Ser51		 ion-based
K +31 Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Glu213 <->
Bridging ionNa401
<-> Ser51 ... Thr50		 ion-based
K +31 Ser51 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Thr209 <->
Bridging ionNa402
<-> Glu54 ... Ser51		 ion-based
K +31 Ala47 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Thr50 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Thr50 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Ala47 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Glu213 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Glu213 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Thr209 <->
Bridging ionNa402
<-> Glu54 ... Ala47		 ion-based
K +31 Met1 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Glu213 <->
Bridging ionNa401
<-> Ser236 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Thr50 <->
Bridging ionNa402
<-> Thr209 ... Asp121 <->
Bridging ionSr404
<-> Ile118 ... Ser77 <->
Bridging ionNa403
<-> Ser210 ... Glu213 <->
Bridging ionNa401
<-> Ser236 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Ser77 ... Ile118 <->
Bridging ionSr404
<-> Gly122 ... Ser210 <->
Bridging ionNa403
<-> Ser77		 ion-based
K +31 Met1 ... Glu54 <->
Bridging ionNa402
<-> Thr209 ... Gly122 <->
Bridging ionSr404
<-> Ile118 ... Ser77 <->
Bridging ionNa403
<-> Ser210 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Glu54 <->
Bridging ionNa402
<-> Thr209 ... Gly122 <->
Bridging ionSr404
<-> Ile118 ... Ser77 <->
Bridging ionNa403
<-> Ser210 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Thr50 <->
Bridging ionNa402
<-> Thr209 ... Gly122 <->
Bridging ionSr404
<-> Ile118 ... Glu54 <->
Bridging ionNa403
<-> Ser210 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Thr50 ... Ser51 <->
Bridging ionNa401
<-> Ser236 ... Ser210 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Gly122 ... Thr209 <->
Bridging ionNa402
<-> Thr50		 ion-based
K +31 Ser51 <->
Bridging ionNa401
<-> Ser236 ... Ser210 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Gly122 ... Thr209 <->
Bridging ionNa402
<-> Glu54 ... Ser51		 ion-based
K +31 Met1 ... Thr50 <->
Bridging ionNa402
<-> Thr209 ... Gly122 <->
Bridging ionSr404
<-> Ile118 ... Ser77 <->
Bridging ionNa403
<-> Glu54 ... Ser51 <->
Bridging ionNa401
<-> Ser236 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Ser51 ... Ile118 <->
Bridging ionSr404
<-> Gly122 ... Glu213 <->
Bridging ionNa401
<-> Ser51		 ion-based
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Glu54 <->
Bridging ionNa402
<-> Thr209 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Ala47 ... Glu54 <->
Bridging ionNa403
<-> Ala206 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Thr50 <->
Bridging ionNa402
<-> Glu54 ... Asp121 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Thr50 ... Ser77 <->
Bridging ionNa403
<-> Thr209 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Met1 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Glu213 <->
Bridging ionNa401
<-> Ser236 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Thr50 <->
Bridging ionNa401
<-> Glu213 ... Ala206 <->
Bridging ionNa403
<-> Ser77 ... Glu54 <->
Bridging ionNa402
<-> Thr50		 ion-based
K +31 Thr50 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Ser77 ... Thr209 <->
Bridging ionNa402
<-> Thr50		 ion-based
K +31 Ala47 <->
Bridging ionNa401
<-> Ser51 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Glu213 <->
Bridging ionNa401
<-> Thr50 ... Ala47		 ion-based
K +31
Chain closureMet1 <-> Met301
... Ser236 <->
Bridging ionNa401
<-> Ser51 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Thr209 <->
Bridging ionNa402
<-> Thr50 ... Met1		 probabilistic
K +31
Chain closureMet1 <-> Met301
... Ser236 <->
Bridging ionNa401
<-> Ser51 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Glu213 <->
Bridging ionNa401
<-> Thr50 ... Met1		 probabilistic
K +31 Ala47 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 <->
Bridging ionNa401
<-> Ser236 ... Ser210 <->
Bridging ionNa403
<-> Ser77 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Thr50 ... Ala47		 ion-based
K +31 Thr50 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Thr50 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Met1 ... Gly122 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Glu213 <->
Bridging ionNa401
<-> Ser236 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Glu54		 ion-based
K +31
Chain closureMet1 <-> Met301
... Ser236 <->
Bridging ionNa401
<-> Ser51 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Thr50 ... Met1		 probabilistic
K +31 Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Ser236 <->
Bridging ionNa401
<-> Ser51 ... Thr50		 ion-based
K +31 Ser51 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Glu213 <->
Bridging ionNa401
<-> Ser51		 ion-based
K +31 Ala47 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Ser236 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Ala47 ... Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Glu213 <->
Bridging ionNa401
<-> Ala47		 ion-based
K +31 Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Thr209 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Thr50 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ... Ser236 <->
Bridging ionNa401
<-> Thr50		 ion-based
K +31 Thr50 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp127 ... Thr209 <->
Bridging ionNa402
<-> Thr50		 ion-based
K +31 Ala47 <->
Bridging ionNa401
<-> Ser51 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Thr209 <->
Bridging ionNa402
<-> Thr50 ... Ala47		 ion-based
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Ser51 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Thr50 <->
Bridging ionNa402
<-> Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Glu213 <->
Bridging ionNa401
<-> Ser51 ... Thr50		 ion-based
K +31 Met1 ... Thr50 <->
Bridging ionNa402
<-> Thr209 ... Ser210 <->
Bridging ionNa403
<-> Ala206 ... Asp121 <->
Bridging ionSr404
<-> Ile118 ... Ser51 <->
Bridging ionNa401
<-> Glu213 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Met1 ... Ala47 <->
Bridging ionNa401
<-> Thr50 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Ala206 <->
Bridging ionNa403
<-> Ser210 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Ala47 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Thr209 <->
Bridging ionNa402
<-> Thr50 ... Ala47		 ion-based
K +31 Ala47 <->
Bridging ionNa401
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Glu54 ... Ile118 <->
Bridging ionSr404
<-> Asp121 ... Thr209 <->
Bridging ionNa402
<-> Thr50 ... Ala47		 ion-based
K +31 Met1 ... Glu54 <->
Bridging ionNa402
<-> Thr209 ... Asp121 <->
Bridging ionSr404
<-> Ile118 ... Ser77 <->
Bridging ionNa403
<-> Ser210 ... Glu213 <->
Bridging ionNa401
<-> Ser236 ...
Chain closureMet301 <-> Met1
 probabilistic
K +31 Ser77 ... Ile118 <->
Bridging ionSr404
<-> Gly122 ... Thr209 <->
Bridging ionNa402
<-> Glu213 ... Ser210 <->
Bridging ionNa403
<-> Ser77		 ion-based
K +31 Glu54 ... Ile118 <->
Bridging ionSr404
<-> Gly122 ... Ser210 <->
Bridging ionNa403
<-> Glu54		 ion-based
K +31 Thr50 ... Ser51 <->
Bridging ionNa401
<-> Ser236 ... Ser210 <->
Bridging ionNa403
<-> Glu54 ... Ile118 <->
Bridging ionSr404
<-> Gly122 ... Thr209 <->
Bridging ionNa402
<-> Thr50		 ion-based
K +31 Ser51 ... Glu54 <->
Bridging ionNa403
<-> Ser77 ... Ile118 <->
Bridging ionSr404
<-> Gly122 ... Ser236 <->
Bridging ionNa401
<-> Ser51		 ion-based
Chain Sequence
MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGTSLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKNLQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEIE-----NNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRM
Whole chain analysis

  Help Knotoid data interpretation Full screen
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


  Help Knotoid subchains data interpretation Full screen
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 23-248 226 1-22, 249-301 22 53 knot
view details
2.1 43-238 196 239-301 1-8 9-42 8 62 slipknot
view details
2.1 48-245 198 246-301 1-42 43-47 42 55 slipknot
view details
2.1 50-250 201 251-301 1-47 48-49 47 50 slipknot
view details
2.1 53-251 199 252-301 1-49 50-52 49 49 slipknot
sequence length 301
structure length 296
publication title Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger.
pubmed doi rcsb
molecule tags Membrane protein
molecule keywords Uncharacterized membrane protein MJ0091
source organism Methanocaldococcus jannaschii (strain atcc 43067 / dsm 2661 / jal-1 / jcm 10045 / nbrc 100440)
missing residues 152-156
total genus Genus: 127
ec nomenclature
pdb deposition date 2016-04-17
KnotProt deposition date 2018-10-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.58.1130 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase; Chain G, domain 1 Methane Monooxygenase Hydroxylase; Chain G, domain 1 5jdqA01
1.20.1420.30 Mainly Alpha Up-down Bundle A middle domain of Talin 1 A middle domain of Talin 1 5jdqA02
5JDQA 5HYAA 5JDHA
chains in the KnotProt database with same CATH superfamily
5JDQA 5HYAA 5JDHA
chains in the KnotProt database with same CATH topology
5JDQA 5HYAA 5JDHA
chains in the KnotProt database with same CATH homology

  
#chains in the KnotProt database with same CATH superfamily
 5JDQ A;  5HYA A;  5JDH A; 
#chains in the KnotProt database with same CATH topology
 5JDQ A;  5HYA A;  5JDH A; 
#chains in the KnotProt database with same CATH homology
 5JDQ A;  5HYA A;  5JDH A;
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling