5LLPA

Crystal structure of human carbonic anhydraseisozyme xii with 3-[(1s)-1,2,3,4-tetrahydronapthalen-1-ylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide
Knot K +31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 26-256 231 1-25, 257-260 25 4 knot
Chain Sequence
KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFS
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
2.1 10-255 246 1-9 260-260 256-259 9 1 slipknot
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2.1 24-257 234 258-260 1-10 11-23 10 2 slipknot
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3.1 25-257 233 258-260 1-23 24-24 23 2 slipknot
sequence length 260
structure length 260
publication title Crystal structure of human carbonic anhydraseisozyme XII with 3-[(1S)-1,2,3,4-Tetrahydronapthalen-1-ylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide
rcsb
molecule tags Lyase
molecule keywords Carbonic anhydrase 12
source organism Homo sapiens
total genus Genus: 73
ec nomenclature
pdb deposition date 2016-07-28
KnotProt deposition date 2017-08-28
Image from the rcsb pdb (www.rcsb.org)
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