5N61 | KnotProt

Cysteine knot

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Help Cysteine knot data interpretation Full screen

				Loop	Piercing
view details				102-c-105-b-236-c-233	102-b-105

Chain Sequence

MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITLS--------------------------------STLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGSTYILSTEVKNILDTVFRKEQCVLQYVFHSRPN-------------------------------------------LSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLQKDKVSLEDRRVIFSRLMNAFVTIQNDVNAFIDSTKAQGRTSGKVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKLFKSSDGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMANVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTERSYVIHMRFFDNNE------------YSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAA-------------DTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGI-------------------------------------------------------------------------------------------------------TSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPN

sequence length	1662
structure length	1459
publication title	Structural Basis of RNA Polymerase I Transcription Initiation. pubmed doi rcsb
molecule tags	Transferase
molecule keywords	DNA-directed RNA polymerase I subunit RPA190
source organism	Saccharomyces cerevisiae
missing residues	142-173, 269-311, 1201-1212, 1275-1287, 1338-1440
ec nomenclature
pdb deposition date	2017-02-14

Image from the rcsb pdb (www.rcsb.org)

None 4C3HA 4C3IA 4C3JA 5G5LA 5LMXA 5M3MA 5M5WA
similar chains in the KnotProt database (40% sequence similarity)

4YM7AA 5M3FA
similar chains in the pdb database (40% sequence similarity)

#similar chains in the KnotProt database (40% sequence similarity)

#similar chains, but unknotted
5M5W A; 
#similar chains in the pdb database (40% sequence similarity)
4YM7 AA; 5M3F A;

5N61A

Cysteine knot

Chain Sequence