5TT8A

Crystal structure of the complex of helicobacter pylori alpha-carbonic anhydrase with benzolamide
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 36
Knot K +31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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+31 24-212 189 1-23, 213-217 23 5 knot
Chain Sequence
ENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDKADLQFKYAASK--AVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHLV-------LAIGFEEGKENPNLDPILNFKEVALDA-------FLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAE
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1 17-194 178 1-16, 195-201 16 7 knot
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3.1 22-197 176 198-201 1-16 17-21 16 3 slipknot
sequence length 217
structure length 201
publication title Structure-Activity Relationship for Sulfonamide Inhibition of Helicobacter pylori alpha-Carbonic Anhydrase.
pubmed doi rcsb
molecule tags Lyase
molecule keywords Alpha-carbonic anhydrase
source organism Helicobacter pylori (strain atcc 700392 / 26695)
missing residues 49-50, 105-111, 132-138
total genus Genus: 36
ec nomenclature
pdb deposition date 2016-11-02
KnotProt deposition date 2017-09-13
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the KnotProt database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the KnotProt database (?% sequence similarity)
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#similar chains, but unknotted
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How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling