5TX4B

Derivative of mouse tgf-beta2, with a deletion of residues 52-71 and k25r, r26k, l51r, a74k, c77s, l89v, i92v, k94r t95k, i98v single amino acid substitutions, bound to human tgf-beta type ii receptor ectodomain residues 15-130
Cysteine knot
Loop Piercing
view details
44-c-48-b-91-c-89 15-b-58
Chain Sequence
ALDAAYCFRNVQDNCCLRPLYIDFRKDLGWKWIHEPKGYNANFCAGACPYRASKSPSCVSQDLEPLTIVYYVGRKPKVEQLSNMIVKSCKCS
sequence length 92
structure length 92
publication title An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
pubmed doi rcsb
molecule tags Transferase/cytokine
molecule keywords TGF-beta receptor type-2
source organism Homo sapiens
ec nomenclature
pdb deposition date 2016-11-15
Image from the rcsb pdb (www.rcsb.org)
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