5TX6A

Structure of tgf-beta2 derivative with deletion of residues 52-71 and 10 single amino acid mutations (mmtgf-beta2-7m)
Cysteine knot
Loop Piercing
view details
44-c-48-b-111-c-109 15-b-78
Chain Sequence
ALDAAYCFRNVQDNCCLRPLYIDFRKDLGWKWIHEPKGYNANFCAGACPK----SPSCVSQDLEPLTIVYYVGRKPKVEQLSNMIVKSCKCS
sequence length 92
structure length 88
publication title An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
pubmed doi rcsb
molecule tags Cytokine
molecule keywords Transforming growth factor beta-2
source organism Mus musculus
missing residues 50-53
ec nomenclature
pdb deposition date 2016-11-15
Image from the rcsb pdb (www.rcsb.org)
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