5U8RA

Structure of the ectodomain of the human type 1 insulin-like growth factor receptor
Warning
  • Chain breaks within knot 31 (displayed as a gray area on the plot and as '-' on the sequence). The broken part of the chain has been replaced by a straight segment, which may affect what knot types are detected - be careful with interpreting results.
Genus: 147
Slipknot S -31

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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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-31 608-749 142 1-317, 773-877 318-607, 750-772 317 105 slipknot
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-31 578-749 172 1-294, 773-877 295-577, 750-772 294 105 slipknot
Chain Sequence
EICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKA---RSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLCPGCEK-------TTINNEYNYRCWTTNRCQKMCPSTCGKRACTENNECCHPECLGSCSAPDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYNSWNMVDVDL--------PPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKDKIPIRKEKEEAEYRKVFENFLHNS---------------------------------------IFVPREYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEG-------------------ADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAK
Whole chain analysis

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Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1


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Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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2.1m 564-669 106 1-563 680-801 670-679 563 122 slipknot
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2.1m 513-688 176 1-7, 700-801 8-512, 689-699 7 102 slipknot
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2.1m 579-689 111 1-572, 697-801 573-578, 690-696 572 105 slipknot
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1.1m 586-690 105 1-578, 697-801 579-585, 691-696 578 105 slipknot
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2.1m 596-671 76 1-583, 679-801 584-595, 672-678 583 123 slipknot
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2.1m 595-690 96 1-583, 699-801 584-594, 691-698 583 103 slipknot
How to cite
KnotProt | Interdisciplinary Laboratory of Biological Systems Modelling