5VQPA

Crystal structure of human pro-tgf-beta1
Cysteine knot
Loop Piercing
view details
293-c-297-b-360-c-358 264-b-327
Chain Sequence
TSKTIDMELVKRKRIEAIRGQILSKLRLASPPSQGEVG--PLPEAVLALYNSTRDRVAGADY----------YAKEVTRVLMVETHNEIYDKFKQSTHSIYMFFQTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSQNSWRYLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCDSRDNTLQVDINGFTTGRRGDLATIHGMNRPFLLLMATPLERAQHLLDTNYCFSSTEKN--------CCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPLALPGASAAPCCVPQALEPLP------------IVYYVGRKPKVEQLS-----NMIVRSCKCS
sequence length 359
structure length 322
publication title Prodomain-growth factor swapping in the structure of pro-TGF-beta 1.
pubmed doi rcsb
molecule tags Cytokine
molecule keywords Transforming growth factor beta-1
source organism Homo sapiens
missing residues 38-39, 60-69, 241-248, 297-308, 312-316
ec nomenclature
pdb deposition date 2017-05-09
Image from the rcsb pdb (www.rcsb.org)
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