5ZD5D

Sf3b spliceosomal complex bound to e7107
Knot K -31
Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
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-31 16-62 47 1-15, 63-85 15 23 knot
Chain Sequence
DLIFCRKQAGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVICGGPGVSDAYYCKECTIQEKDRDGCPKIVNL
Whole chain analysis
Subchain analysis 

Knotoid cutoff: 0.5


Knotoid matrix content: 1

Knot core range Knot core length Knot tails range Slipknot tails range Slipknot loops range N-end length C-end length Type
view details
3.1m 13-70 58 1-12, 71-85 12 15 knot
view details
2.1m 13-62 50 1-12 71-85 63-70 12 15 slipknot
sequence length 85
structure length 85
publication title The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action
pubmed doi rcsb
molecule tags Splicing
molecule keywords Splicing factor 3B subunit 5
source organism Homo sapiens
ec nomenclature
pdb deposition date 2018-02-23
KnotProt deposition date 2018-03-21
Image from the rcsb pdb (www.rcsb.org)
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